Exophthalmus. Wide palpebral slits. Tachycardia. Nervousness. Tremors. Stelwag's sign. Scanty and frequent menstruation. Emaciation. Periodic loss of flesh and strength. Mild hyperthermia. Increased basal metabolism. Lymphocytosis. Von Graefe's sign. Anginoid attacks. Hyperidrosis. Deformities of the nails. Dryness of the mouth. Excessive salivation. Vomiting attacks. Diarrhea. Irregular breathing. Eosinophilia. Increased coagulation time. Increased emotional irritability. Ideas of reference and persecution. Manic symptoms. Bluish-white teeth. High hair line. Hourglass contraction of the stomach. _Symptoms of So-called Hyposecretion_ Precocious graying of the hair. Drowsiness. Anorexia. Small stature. Puffiness of the face. Sallow complexion. Scanty hair. Deepset eyeballs. Dull and listless cornea. Hard, brittle nails. Scanty eyebrows. Cold, bluish, moist hands. Tending to chilblains. Irregularly developed teeth which decay easily. Defective development. Dry, thick, scaly skin. Acrocyanosis. Localized transitory edema. Urticaria. _Parathyroid Stigmata_ Intermittent cramps. Twitching of the hands. Tetany with associated symptoms. _Pituitary Stigmata_ Greatly thickened nose. Prominence of superciliary ridges. Tendency to increased tuftings of terminal phalanges. Coarse, heavy, overhanging eyebrows. Protruding thick lips. Prominent hypertrophied lower jaw. Increased sugar tolerance. Increased interdental spaces. Enlarged sella tursica. Hypertrophied nails. Hypertrophied, thickened skin. Short, square hands. High carbohydrate tolerance. Amenorrhea. Visceroptosis. _So-called Deficiency Symptoms_ Adiposity. Fat pads around the malleoli. Increased development of the mammary glands. Deposit of fat around the buttocks and the neck. Alabasterlike skin. Irregular menstruation. Subnormal temperature. Wide intercostal angle. Fatigability. Infantile uterus. Slow pulse. Sluggish mentality. Mononucleosis. Eosinophilia. Leucocytosis. Short stature. Childlike voice. Bitemporal headache. Supraorbital headache. Sterility. _Adrenal Stigmata_ Aggressive type of individual. Increased growth of hair on body. Masculine type of female and vice versa. Prominent canine teeth. _So-called Deficiency Symptoms_ Asthenia. Low blood pressure. Muscular pains. Fatigability. Pigmentation. Sergent's white line. _Thymus Stigmata_ Very long stature. High palatal arch. Infantile epiglottis. Lymphocytosis. General glandular enlargement. Abnormally long thorax. Visceroptosis. Eosinophilia. _Gonadal Stigmata_ Hermaphroditism. Pale, anemic skin. Flushes in the female. Scanty growth of lanugolike hair. Sparse eyebrows. Dull, lethargic mentality. Characteristic pyramidal pubic hair in males and flat in females.