This poor little boy, in whom all the tragedy of the Tudors seems to have concentrated itself, was born to Henry VIII and Queen Jane Seymour in 1537. Henry had already forgiven himself for his conduct to Anne Boleyn, and was deeply attached to his new queen; during the progress of the christening he sat by the side of his wife and held her hand in order that she might not be too exhausted by the strain. She, poor thing, had to wear a great gown of ermine, and to sit upright on a state pallet to welcome and bless her little son as the service terminated. But her loving arms could not save him; already within him were implanted the seeds of death, a tuberculous tendency from his grandfather, Henry VII, and actual spirochetes from his father, Henry VIII. And, as Queen Jane clutched him to her bosom, she herself began to shiver; no doubt she thought her shivering was from fear lest she lose her son; but within a week of his birth she lay dead, probably from puerperal septicæmia. Henry was heart-broken; but at least the curse of the Church had been lifted; he could now honestly say that he had begotten a legitimate and living son, and that the succession of the English throne was safe. Where the brilliant little Anne Boleyn had failed, this commonplace and featureless Queen Jane, so colourless that everybody liked her, or at least did not hate her, had succeeded. So she being dead, Henry at once communicated with the Court of France in order to get him another wife, if possible; that the Pope might see how impotent he was to affect human destiny. This was not because he was incurably lustful, but because it was still important to have another heir, should little Edward turn sick and die. Already, one thinks, the English Prometheus was scaling Olympus with determined, though engrossed, footsteps; already Zeus might well tremble at the ponderous footfalls of this fat and syphilitic man. But little Edward did not seem likely to die; for, to all appearances he was a strong and healthy little boy. If the Court of England had purposely meant to deny that Edward was syphilitic it could not have chosen better words to do it in, for, as the message announcing the glad news of his progress said, “he sucketh like a child of puissance.” In the typical infantile hereditary syphilis the baby suffers from “snuffles,” and its sucking powers are, to say the least, inadequate. But the spirochæte has other ways of taking its revenge upon its host. It may lie latent for years, and so poison the child’s resisting powers that he falls an easy victim to some deadly bacterium. In the case of little Edward it seems to have been the tubercle bacillus that first seized upon its chance; and when, fifteen years later, just after puberty, it was working its deadly will upon him the spirochæte of syphilis joined the assault.