An attack of erysipelas, strictly limited to the district of the painful nervous branches, then set in. From that moment the neuralgic attacks became less frequent and severe. A second similar onset of erysipelas occurred some three or four weeks after the first. Finally, the neuralgia disappeared about four months after its first occurrence, and the menses reappeared in tolerable abundance about the same time. About a fortnight before this the patient had discovered that her right eye was dim; as the photophobia had previously disabled her from opening the eye, she could not be sure how long this dimness had existed. At the time of her visit to me the cornea was blurred with a large patch of interstitial lymph, with the remains of a superficial ulcer in the centre; the iris was turbid and discolored, showing the traces of recent but past iritis; the pupil was regular in form and active to light; the conjunctiva was slightly congested. Ophthalmoscopic observation was attempted by a skilled observer, but could not be satisfactorily carried out, from the turbid state of the media. The conjunctiva was slightly congested. In place of the lachrymation that had prevailed during the neuralgic period, there was a remarkable insensibility of the lachrymal apparatus, for the patient had noticed that the smell of onions, which would make the other eye weep profusely, had no influence on the affected one. The family history of this patient is a most remarkable one. All the members of her mother's family, for two generations back, had died at middle age, either from apoplexy or some disease involving hemiplegia. This case has, by a mistake, not been added to the list of twenty-two private cases in which the family history was carefully investigated, that will be found in the chapter on Pathology; this arose from the fact that the patient was not properly under my care, but was sent to me as a medical curiosity; the notes of her case were therefore taken in a different book from the others. The case certainly ought to be taken as a counterpoise to such a one as No. XVI. in the list, which is that of a gentleman who suffered from the most complicated neurotic maladies (asthma, angina pectoris, facial neuralgia, more than once attended with erysipelas), but whose family history, so far as it was known, presented no traces of tendency to neurotic disease. To these two cases of inflammation, secondary to neuralgia, I shall add a third, which is even more interesting, and which came under my notice not long since.