Neurosyphilis : $b Modern systematic diagnosis and treatment presented in one hundred and thirty-seven case historiesSouthard, Elmer Ernest
Science
Neurosyphilis : $b Modern systematic diagnosis and treatment presented in one hundred and thirty-seven case histories
Southard, Elmer Ernest
Neurosyphilis
Quiet and orderly at first. Later restless and noisy. Questions were
answered at times relevantly, more often irrelevantly. Patient
irritable, intractable. Required repeated urging to take nourishment.
Consciousness clouded. Orientation imperfect. Attendants are possibly
“officers.” Date September, 1995. Slight errors in repeating alphabet.
Mistakes in Lord’s Prayer with rhyming tendency. Simple arithmetical
tests answered automatically with many mistakes. More complex
combinations incorrect. Handwriting tremulous (noted as “typical of
general paresis”). Auditory hallucinations (answering invisible
persons), “All right, I’m coming.” Amnesia and confabulation. Q. “Have
you had breakfast?” A. “No,” (later) “Yes, I had a very light
breakfast.” Q. “What did you have?” A. “Anything that came along. A few
green peas and beans that were left, bread and butter and pie. I had a
good breakfast. Guess feed is very high.” Q. “Give names of your sisters
and brothers.” A. “There are three or four I never see. I will have to
think them up.” (Later)—“Lillie, Abbie, Julia, George.” On repetition of
question, “Elizabeth, Julia, Annie and Lizzie.”
Delusions somewhat doubtful. At no time euphoria.
The patient remained only nine days in the hospital, developing diarrhea
a week after admission.
=Post Mortem Findings.= The =cause of death= was bilateral
bronchopneumonia of hypostatic distribution, accompanied by bronchitis
and acute splenitis. The intestinal tract was normal (despite the
diarrhea). No cultures. The heart showed acute myocarditis.
The vessels in general showed no sclerosis, except that the aorta showed
a few patches with calcification near bifurcation. There was a moderate
degree of mitral sclerosis. The kidneys showed a moderate degree of
chronic interstitial nephritis. The heart weighed 530 grams and there
was moderate dilatation of all the valves.
There were some evidences of chronic disease outside the nervous system,
namely, an obliterative pleuritis on the right side, chronic
perisplenitis, and chronic external adhesive pachymeningitis.
The =nervous system= showed a pia mater thin and transparent, with a
moderate congestion of larger and smaller vessels. No noteworthy change
of the brain substance or of the ventricles was found, except that the
cerebral substance was of unusual firmness (autopsy twelve hours after
death).
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