Neurosyphilis : $b Modern systematic diagnosis and treatment presented in one hundred and thirty-seven case historiesSouthard, Elmer Ernest
Science
Neurosyphilis : $b Modern systematic diagnosis and treatment presented in one hundred and thirty-seven case histories
Southard, Elmer Ernest
Neurosyphilis
The picture presented by the meninges was scarcely what might be
expected. Although numerous mononuclear phagocytic cells are everywhere
found, yet the predominant picture is that of a polynuclear exudation.
The polynuclear leucocytes occur in greatest numbers in the tissue
spaces, especially in the meshes of the lumbar arachnoid and in the
spaces of the frontal and paracentral pia mater. In the lumbar region of
the spinal arachnoid wide fields occur in which the cells are almost one
hundred per cent polynuclear leucocytes. In places phagocytic cells
occur, and in a few fields, even in the open tissue spaces, the number
of phagocytic cells may arise to fifty per cent. Edema is a considerable
feature in the meninges. Fibrin is found chiefly in the cerebral
meninges and appears in numerous delicate strands in the tissue spaces.
Moloch, horrid king, besmeared with blood
Of human sacrifice, and parents’ tears;
Though, for the noise of drums and timbrels loud,
Their children’s cries unheard that passed through fire
To his grim idol.
Paradise Lost, Book I, lines 392–396
IV. MEDICOLEGAL AND SOCIAL
=Neurosyphilis in a public character: eloquence, reformatory
efforts, notoriety.=
=Case 83.= Major Isaac Thompson, M.D., was a character. He had been
regarded as eccentric for many years prior to his death at 63. In fact,
it seems that there had been more or less definite symptoms and signs
about his fortieth year. The doctor himself had a ready explanation for
his Argyll-Robertson pupils; he explained that he had had a peculiarly
heavy smallpox at about the age of 27 (which would be about 1872).
The doctor had a good secondary education, he had gone through the Civil
War as a hospital steward, went into business after the war, married,
and then went to the medical school, graduating at the age of 34. He
continued in practice for a dozen years, and then gave it up. For years
he had been especially interested in certain literary lines and he had
published any number of pamphlets, all of a somewhat striking
description, often with a political color and intended to stir up reform
measures. The doctor never bore a very good reputation, and years later
it was recalled that certain books disappeared from libraries and their
loss was almost certainly traced to Dr. Thompson. In general, however,
he was considered to be a rather worthy local figure.
Public-domain text, read in full here on John Shaqi.
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