(This paper was arranged from the provings by Dr. W. H. A. Fitz for the Organon and Materia Medica Society of Philadelphia, and published in the _Medical Advance_, 1891) We think of this remedy for the following clinical indications: Hypochondriasis, mania, epilepsy. Amblyopia, cataract, spots on the cornea. Syphilis, hepatitis and indurated liver, visceral obstruction, inflammation of rectum (horses), hemorrhoids, inflammation of kidneys, gleet, copious urination (horses), gravel, syphilis with deranged mind, nosebleed, pain in small of back, gonorrhoea, amenorrhoea, cancer of mammea, sterility (cows), consumption, lumbago, itching, gout, bloody sweat (murrain of calves), dropsy, ill-conditioned ulcers, snake bites and hydrophobia, promotes the expulsion of splinters, inflammation of stomach (horses). It is characterized by great tickling and itching. We find tickling and pricking in the urethra, in left ear; on tip of nose; at soft palate as from something cold; in symphysis pubis; as from a brush against epiglottis (with hoarseness); pain in right leg and at os illium; itching on vertex and occiput; of eyelids; in left ear; on cheek bones; itching and tickling stitches on left corner of mouth and upper lip; in rectum; at anus after evacuation of bowels; on left side of chest, principally on nipple; on neck and scapula; on inside of upper arm, just above elbow joint; on back of right hand; tetter on hands and fingers. In fact, great itching all over the skin. HEADACHE just over supra-orbital ridges, with eructations and rumbling in bowels; spasmodic lancination in temples, extending to eyes; pressive aching in forehead and occiput from a current of air blowing on him; intense headache and nausea, with pains throughout the body. Occiput: dull or tearing pains and inclination to vomit; violent headache, with hard, knotty stools; knocking pains in left side; dull pain all night. PAINS: Teeth pain as from cold. STITCHES: In scalp, over left ear and on occiput; in eyeballs; in temples; in left corner of mouth; in right ear; in left side, region of fourth and fifth ribs; in left tibia, when sitting, when moving leg or foot; disturb sleep. NEURALGIC PAINS: In right cheek bones. Rheumatic, gouty pains. TEARING PAINS: In occiput; in right cheek bone; in upper molars; in spermatic cords; in muscles of left leg; disturb sleep. DRAWING PAINS: In right testicle and cord; tensive drawing in left shoulder to neck, returns when lifting or stretching arms; in muscles of upper arm; especially when moving hands or arm in writing; in right carpal and metacarpal bones (sometimes left), returning at regular intervals; also tearing; in muscles of left leg. PRESSING PAINS: In forehead and occiput; with stitching in eyeballs; in eyes; on lungs; in sacrum. DULL PAIN: In occiput; in hollow tooth, with trembling of heart; in upper molars; in gums, accompanied by hard stools. CRAMPS: In right thenar; ceasing there as it goes to the left.