From symptoms Nos. 5, 6, 7, 8, 14, 15, 23 it would appear the time of aggravation is at night, and the most prominent sensation is _itching_ and less prominent is burning. This is characteristic of the _Arsenicum_ eruption, also of _Anacardium_, _Rhus tox._, and some others. The eruption also bears a strong resemblance to these remedies, and if one may judge from the symptoms enumerated ought to prove a potent rival in erysipelas and eczematous complaints. _Rhus_ poisoning will no doubt find a new and efficient remedy in _Primula_. PYRUS AMERICANA. NAT. ORD., Rosacæ. COMMON NAME, Mountain ash. PREPARATION.--The fresh bark is macerated in twice its weight of alcohol. (We find the following in the _American Observer_, 1878, credited to _Northwestern Analist_ and written by Dr. H. P. Gatchell. Allen, in the _Encyclopædia_ has not mentioned the drug, and we can find no mention in any of the dispensatories consulted. Dr. Fernie, in his excellent book, _Herbal simples_ devotes some space to it. We quote: "'There is,' says an old writer, 'in every berry the exhilaration of wine, and the satisfying of old mead; and whosoever shall eat three berries of them, if he has completed a hundred years, he will return to the age of thirty.' At the same time it must be noted that the _leaves_ of the Mountain ash are of a poisonous quality, and contain prussic acid like those of the laurel." The following is Dr. Gatchell's paper, the proving, be it noted, is made from a tincture of the bark:) My memory of details, never remarkable, except as the details belonged to some system, is not as good as in earlier life, and in the matter of disconnected or partially connected incidents, the widow Bedott could, at any time, have given me five points in ten, and then have beaten me easily. No. 1 of the provers was a married lady; No. 2 and No. 3 were lads. The tincture of the bark was used, several drops being put in a cup of water, of which teaspoonful doses were given and repeated at, I do not remember what, intervals. Myself experienced some irritation of the eyes; no other symptoms.