H. T., male, aged thirteen years. Idiopathic epilepsy; had his first spell when five years of age; averages one paroxysm daily. The _Solanum_ was first given in 10 drop doses _t. i. d._ without effect. When increased to 25 drops the spells were lighter in severity, but occurred about as often. The dose was finally increased to a teaspoonful four times daily. After being put upon this dose he was under observation six weeks, during which time he had six seizures much lighter in severity. T. H., male, aged twenty-eight years. He had epileptic seizures for the past three years. They followed an injury to the head which rendered him unconscious, but produced no other visible injury. Since this, however, has had almost constant headache. First spell six month after the injury, and have been very frequent since, averaging three to four weekly; they are of ordinary type. _Solanum_ in 40 drop doses three times daily was ordered. Spells at once decreased in frequency and severity. During the last six weeks he was under observation he only had three spells, very mild in type. C. R., male, aged twenty-one years. Epileptic seizures for past three years following an injury. Had been trephined in right parietal region before coming under our observation. After trephining the symptom improved, but got worse again; when seen by us was having one daily. 40-drop doses of _Solanum_ caused diarrhoea, and dose was reduced to 30 drops _t. i. d._, when diarrhoea ceased. Under this treatment he had no spell for two weeks. In the following month he had three spells; was then lost to observation. A. N., male, aged thirty years. First spell one year ago; have since occurred every two weeks; good deal of headache. Ordered _Solanum_ 30 drops _t. i. d._ No spells for one month and headache ceased. He then stopped attendance. J. D., female, aged eighteen years. First spell when thirteen years old; has one spell a month at the time of her menstrual period. About a week before this period was given 40 drops _t. i. d._, and escaped the usual spell. The following month, however, she had one. I. K., female, aged twenty-five years. Nocturnal epilepsy for past three years; about one spell a month. While using 40 drops _t. i. d._ went three weeks longer than usual without a spell. The dose was then increased to 1 fluid drachm _t. i. d._; she then ceased her visits. F. S., female, aged twelve years. First spell five weeks ago; has been having them daily since. _Solanum_ 30 drops _t. i. d._, ordered; this dose was gradually increased to 1 fluid drachm _t. i. d._ During the three months that she was under observation her spells averaged in number about one a week. H. B., male, aged eighteen years. First convulsion at age of ten years; then had none until three months ago; has had general convulsions about once daily since. _Solanum_, 40 drops _t. i. d._, ordered. He was only under observation nine days, having during that time four spells, much milder in character.