A boy of fourteen years of age, who had habitual constipation, took, at the advice of a quack native physician, about three or four ounces of the decoction of its root, which produced profuse diarrhoea. After four or five stools I was called. I saw him weak and dejected, using abusive language to his native physician. His face was very pale. Stools were profuse, frequent, gushing, yellowish, watery. Much pain and cutting about the umbilicus during and before stool. After every stool he felt dizziness of the brain. This case struck me that _Trychosanthes dioica_ will prove a grand remedy for diarrhoea. I prepared its tincture from the root and used it in 3x potency, in some cases with great satisfaction. The following cases will show its curative power: 1. A girl, aged 6 years, was attacked with diarrhoea; stools were profuse, thin, yellowish, watery, mixed with little white mucous; very offensive smell; cutting pain about umbilicus during and after stool. Pain in liver and eyes; jaundice; face yellowish; very weak; did not wish to answer questions: sad and peevish. On the fifth day I was called. I prescribed _Trychosanthes dioica_ 3x every three hours. I saw the patient much better next day. Within a day or two the patient was all right. 2. A boy, aged 16 years, suffering from chronic diarrhoea; passed from four to five stools in a day. The character of the stool was yellowish, watery, mixed with a little white and greenish mucus. Smell offensive; dull, aching pain in the region of the liver. Face very pale; eyes jaundiced. He was very sad and dejected. His appetite little; taste bitter. He had been at first treated by an allopath, then, afterwards, by a homoeopath. The latter showed some improvement. I was called on the thirteenth day, when I noticed the above symptoms. I prescribed _Trychosanthes_ 3x every four hours. The patient was completely cured within four days. I cured some cases of choleric diarrhoea by this medicine, but those cases were vaguely reported to me. I hope that, when proven, _Trychosanthes dioica_ will show its large sphere of action and give our Materia Medica a new remedy for looseness of bowels. USNEA BARBATA. NAT. ORD., Lichens. PREPARATION.--The fresh lichen is macerated in five times its weight of alcohol. (This appeared in No. 284 of the _U. S. Med. Investigator_ signed "---- M. D."): In March, 1878, I was cutting wood. I cut down a soft maple; the top was well loaded with moss. It attracted my attention; I viewed it closely. I ate a little, about the size of a hickory nut, as I trimmed up my tree. My head began to ache. I cut off one log, and had to go to the house. I could feel the blood press to the brain. My wife worked over me, and I got to sleep. Next morning felt well; never felt better. I did not think of the moss I had eaten. I went on a visit and was gone five days. On my return I went to my tree. The first sight of it reminded me of my headache.