"About twelve years ago I was suddenly seized with terrible pain in the left breast; it extended over the entire region of the heart and down the brachial plexus of the left arm as far as the wrist. I pressed my hands over my heart and seemed unable to move. My lips blenched, my eyes rolled in a paroxysm of agony; the most fearful sense of impending calamity oppressed me and I seemed to expect death, or something worse, to fall upon and overwhelm me. The attack lasted a short time and then began to subside, and soon I was myself again, but feeling weak and excited. I consulted no one; took no medicine. I did not know what to make of it, but gradually it faded from my mind and I thought no more of it until two years afterwards, when I had another attack, and again nearly a year later. Each of these was very severe, like the first, and lasted about as long and left me in about the same condition. I remember no other seizure of importance until about three years ago, and again a year later. These were not so terrible in the suffering involved, but the fear, the apprehension, the awful sense of coming calamity, I think, grew upon me. From this time on, two years ago, the attacks came frequently, the time varying from two or three months to two or three weeks between. "I took some nitro-glycerine tablets and some pills of _Cactus Mexicana_, but with no benefit that I could perceive. This brings me down to about fifteen months ago. I was feeling very badly, having had several attacks within a few weeks. My pulse was at times very rapid and weak, and irregular and intermittent. (About this time he got hold of _Cratægus_ with the following result): "After getting my supply I began with six drops, increasing to ten before meals and at bedtime. The results were marvellous. In twenty-four hours my pulse showed marked improvement; in two or three weeks it became regular and smooth and forceful. Palpitation and dyspnoea soon entirely left me; I began to walk up and down hills without difficulty, and a more general and buoyant sense of security and well-being has come to stay. During the three months that I was taking the medicine, which I did with a week's intermission several times, I had several slight attacks, one rather hard seizure, but was relieved at once on taking ten drops of the medicine. (He adds that hypodermic of _Morphia_ does not give relief from these heart pains as quickly and as surely as does fifteen drops of _Cratægus_. He also says, "of course I consider it the most useful discovery of the Nineteenth century." He also names a number of "the most reputable and careful men in the profession," who are having good results with this remedy.) (Dr. T. C. Duncan contributes the following illustrative cases):