An excellent remedy, and one on which the sole dependence should be placed, were we not in possession of one which possesses a decided superiority, is one which was communicated to me by Dr. PARRISH. It is as follows, including a slight correction made by the apothecary: R. Sulph. Zinci, [Symbol: dram]i Aquae, [Symbol: dram]ij Solve. Dein adde, Mellis Despum. et Tinct. Myrrhae, aa [Symbol: ounce]ij To be used in the manner described above. Some bad cases yielded to the following: R. Sulph. Zinci, [Symbol: dram]ij Aquae, [Symbol: ounce]i _m._ It is useful to record failures and unsuccessful trials; as they serve to deter others from unnecessary risk. We therefore record the following as not having succeeded in our hands: R. Mellis et Tinct. Myrrhae, aa [Symbol: ounce]i _m._ The same, with the addition of powdered bark. R. Aluminis, [Symbol: scruple]ij Tinct. Myrrhae, et Mellis, aa [Symbol: ounce]ij _m._ R. Pulv. Cinchonae, [Symbol: ounce]i Myrrhae et Pulv. Carbonis. a [Symbol: ounce]ss _m._ et adde Succ. Limonum, q. s. ad massam faciendam, qua illineantur gingivae. Caustic potassa; and nitrate of silver. Pyroligneous acid, both pure and variously diluted with water. This had but a very limited effect, even in destroying the foetor; and I am by no means sure that it was of any use in arresting the disease. Muriatic acid, though praised by such high authorities, did not seem productive of any distinct useful effects. Nitric acid, variously diluted, and sulphuric acid, which was tried in one case, diluted with an equal quantity of water, were entirely useless. Of _constitutional_ treatment, the disease seemed to admit very little. In the early stage, the means employed, were the same mentioned above as means of prevention. It was by no means evident that any of these were useful in retarding the progress of the complaint. Towards the decline of the worst cases, aromatic sirup of rhubarb, with magnesia, were employed, to remove the putrid matters swallowed; and to relieve the diarrhoea which generally took place, by the astringent operation of the first mentioned medicine. It is extremely doubtful whether these means were productive of any benefit. * * * * *