In that connection, then, I may briefly discuss the present range of the disease so far as we know it, outside of the natural range of the chestnut tree. South of Virginia, so far as we know, the disease is present at only one point (Greensboro, N. C.), where it was introduced in a nursery and spread to native trees. In stating this area of distribution, I ought to say that for about a year and a half we have made no special effort to determine the range of this disease. I mean we have not gone out of our way to do it. We have simply collected such evidence as has come to hand casually, and so it may be that there are now other points of infection in North Carolina, or south of there, but, if so, we do not know of them. In Ohio, the disease is present at three points, of which one is a large and serious infection at Painesville. In Iowa, it is present at one point, Shenandoah, in a nursery. In Indiana, it is present at five points; in Nebraska, at two points. In Michigan, one point has been reported. In all of these cases it is in nurseries, or on very recently planted trees. There is, or was, an interesting point of infection in British Columbia. Probably the trees there are all dead by this time, but that point is very interesting as being probably an independent importation from the Orient. There needs to be little said as to how the disease is spreading in this area. Perhaps the best thing I can do is to read some letters that have come to my attention: "MICHIGAN AGRICULTURAL COLLEGE, "EAST LANSING, "Aug. 18, 1916. "Dr. Haven Metcalf, "U. S. Dept. of Agriculture, "Washington, D. C. "Dear Mr. Metcalf: "Last December, the Forestry Department of this College ordered of Glen Bros., Glenwood Nurseries, Rochester, New York, five 6-foot trees of the Sober Paragon chestnut. These were shipped to them April 4th and were almost immediately planted in the Forestry Nursery here. About six or eight weeks ago, the Forestry Department noticed that these trees were dying and called our attention to this matter about four weeks ago. I examined the trees in company with Mr. J. H. Muncie, one of our assistants, and found all the external appearances of Chestnut Blight with, however, only a very few imperfectly developed pycnidia. We brought pieces of the bark of these trees into the laboratory and made cultures and obtained the typical mycelium of chestnut blight. The trees have been removed and we now have them in our laboratory. "I am calling this to your attention as the trees were doubtless infected when shipped. I feel that you ought to know that this firm is sending out diseased trees. "Very truly yours, "(Signed,) ERNEST A. BESSEY, "Professor of Botany." The following is an extract from a letter from Frank N. Wallace, State Entomologist of Indiana, dated July 13, 1916: "My Dear Sir: