There is reason to think that it is not in the vegetable sweet alone that the antiscorbutic principle resides, but in this in conjunction with the natural mucilage, such as exists in the malt. I suspect likewise that the change which the essence undergoes in its preparation tends also to rob it of some of its original virtue. But the melasses are still farther altered by being deprived of the natural mucilage by means of quick lime, with which all sugar is clarified in the boilers. Dr. Hendy, of Barbadoes, to whom I have been obliged for several remarks, informed me, that the liquor, before it undergoes this operation, has been found by him to produce the most salutary effects in the scurvy; but as this cannot be had at sea, we had no opportunity of comparing it with other antiscorbutics. It is certain also that the medical effects of the native sweet juices are, in other respects, very different from what they are in their refined state; for manna, wort, and the native juice of the sugar cane, are purgative; whereas sugar itself is not at all so[5]. This affords a presumption, that they may be also different in their antiscorbutic quality; and there is reason to think, from experience, that the more natural the state in which any vegetable is, the greater is its antiscorbutic quality. Vegetables, in the form of sallads, are more powerful than when prepared by fire; and I know, for certain, that the rob of lemons and oranges is not to be compared to the fresh fruit. Raw potatoes have been used with advantage in the fleet, particularly by Mr. Smith, of the Triton, who made the scorbutic men eat them, sliced with vinegar, with great benefit. This accords also with what Dr. Mertans, of Vienna, has lately communicated to the Royal Society of London. When the fleet arrived at Barbadoes on the 23d of May, it was found that the number of sick on board amounted to sixteen hundred, and that there was not accommodation for more than two hundred at the hospital. As there was hardly any complaint but scurvy, the Admiral, at my representation, issued an order for serving the sick on board of their own ships with fruit and other vegetables and refreshments, such as milk and soft bread. This course of diet commenced in the beginning of June; and as the greater part of the fleet was near four weeks thereafter in port, they enjoyed the advantages of it during that time; and the very great diminution of sickness and mortality, which appears by the Tables in that month, sufficiently evinces the benefit derived from it. In less than four weeks the fleet, from being very sickly, became extremely healthy.