In the few cases in which epileptic convulsions are occasioned by chloroform, they do not appear till the third degree of narcotism is induced, in this respect differing from hysteria, which comes on in the second degree, or even earlier, as was stated above. The course to pursue, when epileptic convulsions appear, is to continue the chloroform steadily and gently, till they subside. I have never seen the chloroform fail to subdue the convulsions in a very few minutes, and I have never seen them recur after the operation, as the effects of the vapour subsided. In medical and obstetric practice, and for slight operations, it is not requisite to carry the effects of chloroform so far as that stage in which an epileptic fit would occur, so that under these circumstances the fact of a patient being subject to epilepsy hardly requires to be taken into account. _Pregnancy._ I have repeatedly given chloroform at all periods of pregnancy, both for tooth-drawing and more important operations, and I have not met with any ill effects from it in any of the cases. _The Menstrual Period._ It is customary to avoid the menstrual period in fixing the time for a surgical operation, when it can be so arranged. There are, however, often reasons for not waiting over this period, and under such circumstances, I do not know any objection to the inhalation of chloroform. I have administered it frequently during the menstrual period, and have seen no ill effects from it. I have observed that there is a little more tendency to slight hysterical symptoms, during its inhalation at this period, than when the same patients inhale it at other times, which is what we might expect. _Diseases of the Lungs._ Affections of the lungs sometimes cause a little difficulty and delay in the administration of chloroform, as the vapour is liable to excite coughing when the mucous membrane of the air-passages is irritable. The inconvenience is, however, confined to the time of inhalation, for the cough is generally relieved afterwards. I have given chloroform for surgical operations in many cases where phthisis was present, and in several patients who had suffered from hæmoptysis, and have not seen any ill effects from its use in these cases. Chloroform has indeed often been inhaled with advantage to relieve the cough in consumption. The cases of chronic bronchitis in which chloroform is administered for surgical operations are still more numerous. The effects I have observed have been coughing at the time of inhalation, and very often a relief of the cough afterwards. Some of the patients had emphysema of the lungs. It is scarcely necessary to allude, in this place, to acute diseases of the lungs, as surgical operations are not performed during their continuance, but from the fact of chloroform being inhaled occasionally in the treatment of these affections, it is evident that they would cause no obstacle to its employment.