Considering the newness of the strychnine treatment it would be folly to expect that the conditions necessary to insure success should have been observed in every case, and that every practitioner should at once have made himself familiar with it and the theory on which it is founded. Hence a few failures were unavoidable. Of these a record has been kept, but for obvious reasons the writer withholds it here. To give names and dates would be invidious, though the opponents of the treatment have exultingly pointed to the few deaths that have occurred as palpable proofs of its uselessness, some of them even going so far as to ascribe these deaths to the direct action of the antidote. There is, however, not a single case on record, in which death took place under strychnine-convulsions. All the patients died under palpable symptoms of snakebite-poisoning. As these symptoms have now been proven beyond all doubt to yield to strychnine, when properly administered, the inference that it was not so administered in the cases referred to becomes not only justifiable, but unavoidable. In one case only, that of a child of tender years, blood was vomited so copiously that death may be ascribed to that cause and the snake-poison combined, but in all the other six fatal ones, mostly of children, it was undoubtedly due to the snake-poison not being properly checked by the antidote. The gentlemen who officiated on these occasions were evidently not Banerjees, but the very reverse of their Indian confrère. They do not appear to have had very clear ideas of the absolute antagonism existing between the two poisons, and entirely disregarded the most important point in the treatment, namely, the necessity of administering the antidote until it has completely subdued the snake poison, regardless of the quantity that may be required for that purpose. In a few instances the treatment was correct enough at first, but when, as is often the case, a relapse took place after the patient had apparently recovered, the large quantity of the antidote already administered appears to have given rise to the erroneous notion that it would be useless to resort to it a second time, and thus, through this error and the fear of strychnine-convulsions, the patients were allowed to die. In most of the six fatal cases collected by the writer, however, the doses and total quantities given were altogether inadequate to cope with the poison. They did probably more harm than good, for the snake-poison when only partially checked by strychnine seems to renew its onslaught on the nerve-cells even more insidiously than when not interfered with at all. Convulsions also, as shown in cases, are sometimes called forth by this timid use of the antidote.