Not a single attempt has been made to disprove the correctness of the theory on which it is founded, yet to leave this theory unquestioned but object to the conclusion to which it leads, must strike even the lay mind as a most illogical proceeding. It is self-evident that, when strychnine is administered as an antidote to snake-poison, the quantity of it injected must be in proportion to that of snake-venom present in the system, and that the doses in which we dispense it in ordinary practice must be entirely left out of sight. Still, in the face of these obvious conclusions, we have had veterans, grave and grey, arguing pompously that the heroic doses advocated by the writer could not be countenanced, and that even medical men could not be entrusted with the serious task of administering them. Even as late as the last medical congress at Sydney this absurd objection to large doses of the antidote was again brought forward. After quantities averaging from half a grain to a grain have been injected many times in Australia with continuous success, after Banerjee has even gone as high as three and four grains in India without a single failure, and without in one single instance serious strychnine symptoms being evoked, the writer of the paper on "Snakebite and its Cure" based his principal objection to the treatment on the alleged ground of there not being sufficient evidence before us to justify heroic doses and show them to be safe in practice. When people wilfully shut their eyes against the most conclusive evidence, it is improbable that any amount of it would satisfy them. Apart, however, from the fully proven antagonism between the two poisons rendering the large doses of the antidote, which in all serious cases are indispensable, perfectly safe, the fear of strychnine is, in itself, a very strange aberration of judgment on the part of my opponents, considering how easy it is to counteract any noteworthy excess in its action, if, perchance, it should occur through unnecessary overdosing, by appropriate remedies.