In addition to their action on the intestine, some of these salts affect the salivary gland. After the injection of BaCl_{2} there is often so great a flow of saliva that it falls in drops from the mouth. This phenomenon is not constant, however, and seems to follow only large doses. Sodium fluoride has sometimes the same effect. I have not noticed any influence exerted by the other purgative salts upon the salivary secretion. It is further of not infrequent occurrence to have a repeated evacuation of urine after the administration of BaCl_{2}. Although this cannot be attributed to a direct increase of the secretion of urine, it is interesting to note in this connection some later experiments in which it was shown[29] that when the flow of urine in a rabbit had been well established by the injection of m/6 NaCl solution into the circulation, the addition of a minute quantity of BaCl_{2} to the NaCl solution caused a very considerable increase in the secretion of urine from the kidney. A quantity of not more than ¹⁄₈ c.c. m/8 BaCl_{2}, must be given intravenously to produce this effect. If 1 c.c. m/8 BaCl_{2} be injected intravenously at one time the flow of urine suddenly stops. This seems to be due either to a sudden constriction of the musculature of the urinary passages and pelvis of the kidney by which the lumen is cut off, or to a similar constriction of the blood vessels of the kidney. In either case the action of BaCl_{2} in stopping the secretion is mechanical and has to do with its power of causing violent muscular contractions rather than with its capacity for increasing the secretory activity. Although there is apparently one action for BaCl_{2} on the flow of urine when given in small doses and quite the opposite action when it is given in larger quantities, the two actions are in reality quite distinct, one being exerted on the secretory cells of the kidney and the other on the musculature of either the urinary passages or of the blood vessels of the kidney.