_Third case._--Huroo, a female, aged twenty-five, admitted to the Native Hospital on the 16th of December; had tetanus for the three previous days, the sequel of a cut on the left elbow received a fortnight before. Symptoms violent on admission. Turpentine and castor oil given repeatedly without effect; on the 16th and 17th, three grains of hemp resin were given at bed-time. On the morning of the 18th she was found in a state of complete catalepsy, and remained so until evening, when she became sensible, and a tetanic paroxysm recurred. Hemp resumed, and continued in two grain doses every fourth hour. She subsequently took a grain twice daily till the 8th of February, when she left the hospital apparently quite well. Mr. O’Brien has since used the hemp resin in five cases, of which four were admitted in a perfectly hopeless state. He employed the remedy in _ten grain doses_ dissolved in spirit. The effect he describes as almost immediate relaxation of the muscles and interruption of the convulsive tendency. Of Mr. O’Brien’s seven cases four have recovered. In the Police Hospital of Calcutta, the late Dr. Bain has used the remedy in three cases of traumatic tetanus, of these one has died and two recovered. A very remarkable case has recently occurred in the practice of my cousin, Mr. Richard O’Shaughnessy. The patient was a Jew, aged thirty, attacked with tetanus during the progress of a sloughing sore of the scrotum, the sequel of a neglected hydrocele. Three grain doses were used every second hour with the effect of inducing intoxication and suspending the symptoms. The patient has recovered perfectly, and now enjoys excellent health. Beside the preceding cases I have heard of two of puerperal trismus treated in native females. Both terminated fatally, an event which cannot discredit the remedy, when it is remembered that the Hindoo native females of all ranks are placed, during and subsequent to their confinement, in a cell, within which large logs of wood are kept constantly ignited. The temperature of these dens I have found to exceed 120° of Fahrenheit’s scale. A curious coincidental proof of the value of hemp in these cases has very recently come to my notice. In the appendix to Sir James Murray’s “Medical Essays,” p. 16, dated Dublin 1837, occurs the following passage:--“Having written the substance of these pages (Sir James’s work) to my brother, then assistant-surgeon of the 60th Rifles, at the Cape of Good Hope, he mentioned that a plant called _dyka_, or wild hemp, which grows on the eastern coast of Africa, is used by the natives for this purpose (the relief of puerperal convulsions), and that they all, male and female, smoke it to bring on perfect relaxation and relief from pain and spasm of any kind during its relaxing influence.”