During the time we were at Danville, we suffered considerably from cold and close confinement. The small-pox also broke out among us, and attacked a great many, but in most cases in a mild form. Those afflicted had it as violently as could be expected under the circumstances, their systems being in such a depleted condition that the disease had nothing to feed on. In fear of it, and to prevent it, many were vaccinated. I was not,--and I thank Providence that I was not, as I knew some to suffer worse from vaccination than they could have done from the small-pox, even though it terminated fatally; for it did terminate fatally in the cases of vaccination, and after more suffering than could possibly have ensued from the dreaded disease itself. The vaccine virus proved to be poisonous in some cases. I knew a man whose left arm was eaten to the bone by it, the bone being visible, and the cavity, which was circular in shape, was as large in circumference as an ordinary orange. After months of excruciating pain, the man died. But sometimes vaccination did not even prevent the small-pox. A man with whom the writer bunked was vaccinated, and it "took," what would be considered immensely well, a very large scab developing upon each arm. Yet this man took the small-pox, and badly, while the writer,--to take another view of the case,--although he had not been vaccinated for about thirteen years, and yet had been exposed to the disease in almost every way, and had slept with this man while he was taking it, and after he returned from the small-pox hospital with his sores but partially healed up, remained perfectly free of it. I thought if I must have it, I must, and there was an end of the matter; there being no way of avoiding it that I could see; and I do not know but the late vaccination, while the disease was already thickly scattered about the house, increased the danger of contagion by throwing the blood into a fever of the same kind; while by leaving the blood undisturbed, if the disease was not intercepted, the chances of taking it were at least not augmented.