In this natural arrangement, I must again remark, that all its parts correctly correspond and beautifully flow from each other; while anatomy is the basis of physiology, physiology, in its turn, is the basis of medicine; the classification of one is applicable to the rest, and all of them at once involve mineral, vegetable and animal nature. Such arrangement, as it lays the foundation of a new system of each, will, I trust, soon shed some light over anatomical, over physiological, and particularly over the dark paths of medical science; but it must be remembered, that this exhibits merely a sketch of the application of my general arrangement to medical science, and that sketch necessarily brief and deprived of every illustration. Yet, even after this sketch, I think I may add, in the words of Lord Bacon, that “the harmony of a science, supporting each part the other, is and ought to be the true and brief confutation and suppression of all the smaller sorts of objections.” I shall now, however, further explain the principles upon which the natural system is constructed. * * * * * The correctness of this arrangement, as strictly founded on physiology, is confirmed by the following observations. Disease is change of the healthy state and of the healthy action of parts. It is change of the state as well as of the action of parts, because action depends on state, life itself on organization, and it is only by affecting this state—the structure of the objects acting, that change of action can be produced. In fracture, as far as the bone is concerned, the action peculiar to it—loco-motion is affected; as the blood-vessels are ruptured, their action is affected; as the nerves are injured, their peculiar action is also affected. Thus each has its peculiar action, and the action of each is affected through the medium of its structure; but the affection of the state and action of the vessels or nerves is not, in fracture, the primary disease, but only an extension of it to other parts or other functions, or, more properly, they are new diseases, because they affect new functions, and, though dependent upon it, are, in their nature, entirely different from fracture—the primary disease. The action, for instance, of vessels in absorbing, circulating and secreting, so far as, in vegetables, for instance, the form and arrangement of their capillary tubes are concerned, or the continuation of the action commenced in these tubes, or the effusion of their contents when ruptured, is evidently independent of nerves; and I believe, were this principle traced further, it would be found to account for many of the actions of animal as well as vegetable parts. Whether true or false, however, it cannot materially affect the system. For whether their action is dependent on nerves or not, it is, strictly speaking, their own action, and, by injury, they are rendered incapable of performing it.