“The first phase is characterised by intestinal disorder, produced by the development of the larvæ in large numbers, and their adhesion to the mucous membrane of the intestine. In this stage M. Davaine has seen rabbits die with intense diarrhœa; one of two cats which he fed with trichinised meat had diarrhœa for at least a fortnight, but survived. Of five or six rats fed on a similar diet, one only, which was pregnant, died of diarrhœa, after abortion, on the eighth day. According to M. Leuckart, the passage of the embryos of Trichinæ through the intestinal walls sometimes produces peritonitis. This intestinal phase often becomes blended with the next; it may be relieved by the expulsion of the worms by means of the diarrhœa, or may cease with the natural death of the worms. “The second stage presents general symptoms--muscular pains, &c. These phenomena are dependent on the introduction of the Trichinæ into the muscles; they rapidly acquire their maximum intensity, and have not a long duration. The appearance and duration of this stage are in complete relation with the development and length of sojourn of the Trichinæ in the intestines; in fact, in this entozoon, oviposition is not slow and of long duration, as in many nematoid worms; the genital tube is rapidly formed, and the ova, in its whole length, are developed almost simultaneously, so that the embryos, arriving soon at maturity, are at once thrown out in large numbers into the intestine, and the mother Trichina dies exhausted. If it be remembered that the embryos do not escape before the eighth day, that a certain number of days are required for their arrival in the muscles, and that new ones are not produced after six or seven weeks, it will be understood that the first symptoms of this stage can scarcely appear until the end of a fortnight after ingestion of the diseased food, that they must continue four or five weeks, and that after this they may disappear. This course of events is observed in animals; and in man the symptoms of this stage have shown themselves and become aggravated from the third to the sixth week after infection. Most animals die during this stage; rabbits rarely survive; rats, on the contrary, generally resist it. “If the animals do not die of the general symptoms or local disturbances proper to these two stages, the inflammatory symptoms cease, respiration becomes natural, and order is re-established. But, in some cases, the number of cysts formed in the muscles are sufficiently great to impede them in the proper exercise of their functions, and hence arises general debility, a kind of consumption which persists or becomes aggravated, and the animal dies of marasmus. M. Davaine has noticed this in rabbits, but especially in a rat.