On the physical side we found a rather slight girl, however, of normal development. Weight 102 lbs.; height 5 ft. 3 in. No organic defect was ever discovered. Neurological examination showed as follows: No tremors. Tendon reflexes normal. Conjunctival and palatal reflexes absent. The sense of pain to pin pricks was almost nil on the arms, and diminished on the face. Strength poor in the arms even when there was evidently great effort made. (Several of these functional findings, however, have varied from time to time in the ensuing years.) Hearing normal. Ocular examination showed hypermetropia 1.5 D. R. and L. with marked astigmatism. Fields and color vision normal. Left pupil about twice the size of the right. (A competent oculist could find no evidence of organic affection of the nervous system correlated with this.) Shape of head normal. Bowels regular. Appetite capricious. When first seen was anemic, but later color was very good. Temperature was taken regularly, but no significant observations made. Petite, pretty features, and unusually beautiful eyes. Complaint of frontal dull headaches, soreness of scalp, cold hands and pain ``about the heart.'' Menstruated at 15 years, then much irregularity for two years. Several badly carious teeth and great crowding in a narrow upper dental arch. This girl was several times observed during a period of about 5 years. She developed into an unusually attractive young woman, showing at times various mild nervous disturbances as well as character difficulties. Only occasionally has she worn the glasses which corrected her errors of refraction. During this time she has not been severely ill. She has a palpable thyroid which has hardly increased in size. When last seen she was notable for a very clear skin, good color, and bright eyes. Conjunctival and corneal reflexes much diminished. Palatopharyngeal reflexes quite absent. The headaches are said to have persisted during all the time we have known her.