Medical literature contains numerous observations of ailment caused by fright, and even of death itself so caused. It is not uncommon for medical students to contract the disease about which they are studying. In the old small-pox epidemics it was a very generally observed fact that those who feared contracting the disease were the most apt to get it. The reason is very easily explained—fear so suppressed the functional activities of circulation and nutrition, as to predispose the individual to take any disease to which she was exposed. Autosuggestion is the predominant element in the concentration of the thought on one particular subject, and of the narrowing of the perspective to a single point of view. Prolonged anxiety or grief will cause an emaciation, second only to that of tuberculosis itself, by the depression of the heart’s action and the circulation, the loss of appetite, the interference with nutrition, and the loss of sleep. Worry is, as we have seen, in the first instance most frequently bred of exhaustion, but, if indulged in, it readily becomes a fixed habit, and the mind rapidly settles into a state of fixed gloom. Worry is a type of fear. It is a futile regret over past mistakes and the miserable forecasting of the future. It has been called the great shortener of life under civilization—of all forms the financial one is the most frequent and, for ordinary minds, the most distressing. Anxiety and the anxious frame of mind is in readiness to take fright in connection with our most vulnerable points on all occasions of apprehension or uncertainty. As no one’s future can be clear throughout, there is never wanting the matter of anxiety to a mind susceptible of this state. It is a significant fact that our asylums are recruited from the classes who spend their lives amid narrow monotonous surroundings; hence the large proportion of women, especially of farmers’ wives, whose lives are probably the most narrow and the most monotonous. From this result the fixed ideas, the obsessions, and all the absorbing egotism of insanity. With a variety of valuable and permanent interests, the mind is well safeguarded against attacks of worry. The overworked woman should increase her recreations, leave home for short intervals, travel, and have entire rest and change of scene. With increased vigor of body will come increased power of the will and the capacity to abolish worry. Anger floods the brain with blood, and if the arteries are brittle, as they are in old age, and the individual is just as old as her arteries, the rise in arterial tension may result in the rupture of a blood-vessel, and the subsequent hemorrhage into the brain may cause an attack of apoplexy, paralysis, or even death. Attacks of anger hasten the deterioration of the arteries; in this way anger has been known to cause death.