Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
by soap, although in prescribing it, its levity should be attended to,
or otherwise the pills will be too bulky; in general it will combine
with an equal portion of any resinous powder, as _Rhubarb_, _Jalap_,
_&c._; it is of course ineligible where the substances are decomposed by
alkalies, as _Tartarized Antimony_; this last precaution will also apply
to _aromatic confection_ as a vehicle, on account of the carbonate of
lime contained in it. The _Conserve of Roses_ has the advantage of
retaining its consistency much longer than mucilage, but as it contains
an uncombined acid, it is frequently inadmissible; it could not for
instance be with propriety employed with the precipitated sulphuret of
antimony. Pills made with mucilage, are apt to crumble when they are
rolled out; this is the case with the _Pilulæ Hydrargyri submuriatis_;
some extract therefore would be a more convenient constituent; in this
particular case, however, the addition of a few drops of spirit would
supersede the necessity of _any_ constituent. Castor oil, in some cases,
especially with some of the harder purgative extracts, will impart an
eligible consistence.
_Crumb of bread_, furnishes a convenient vehicle for those salts which
are ponderous, active in very small doses, or which are liable to be
decomposed by other vehicles; but an objection is attached even to this,
for it is liable to become so dry and hard when kept, that pills made
with it will frequently pass undissolved. Swediaur mentions this fact
with reference to Plenck’s mercurial pill, as well as to one of
corrosive sublimate, and he proposes for this reason to substitute
_starch_; the addition however of a small portion of sugar will prevent
the bread from becoming thus indurated, and with such a precaution it
may be very safely employed. For the purpose of forming active vegetable
powders into pills, such as _Digitalis, Conium_, &c., I am informed by
Mr. Hume of Long Acre, that in his experience _melasses_ or _treacle_ is
the best constituent that can be selected, for it undergoes no
decomposition by time, but maintains a proper consistency, and preserves
the sensible qualities of the plant quite unimpaired for many years. I
have deposited in the cabinet of the College, specimens of such pills,
of _hemlock_ and _foxglove_, which retain the characteristic odour of
these vegetables, notwithstanding they have been now made for several
years. _Honey_ has likewise the property of preserving vegetable
substances; _seeds_ may be kept in it for any length of time, some of
which, on being taken out, washed, and planted, will even vegetate. It
has also been used for the preservation of animal matter; the bodies of
the Spartan kings, who fell at a distance in battle, were thus
preserved, in order that they might be carried home.[298]
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