Pharmacologia: Fourth American, from the Seventh London EditionParis, John Ayrton
Science
Pharmacologia: Fourth American, from the Seventh London Edition
Paris, John Ayrton
Pharmacognosy; Pharmacology; Pharmacy
QUALITIES. _Taste_, moderately bitter, and acrid, leaving in the mouth a
painful sensation of heat and roughness, followed by numbness in the
gums and lips which continues for two or three hours. _Odour_, faint and
narcotic; their peculiar properties are considerably deteriorated by
drying. CHEMICAL COMPOSITION. M. Brandes has ascertained that the
narcotic principle of this plant is a peculiar alkali, to which he has
given the name _Aconita_.[356] SOLUBILITY, water and alcohol only
imperfectly extract their virtues. MEDICINAL USES. It is narcotic, and
occasions, in over-doses, nausea, vomiting, vertigo, hyper-catharsis,
cold sweats, convulsions, and death; effects which entirely depend upon
its action on the brain. It was first administered in 1702, by Stöerk,
of Vienna, in chronic rheumatism, gout, schirrus, and paralysis; more
lately it has been employed in scrofula, cancer, and intermittents, and
it is said with much effect. On account of the variable strength of the
leaves they can hardly be given with safety and effect; the extract
(_which see_,) presents the more eligible form of exhibition. The leaves
are, however, sometimes given in the form of powder, generally combined
with some mercurial alterative, or with antimonials, camphor, and other
diaphoretics. DOSE gr. i-x. OFFICINAL PREP: _Extractum Aconiti._ L.E.
ADEPS PRÆPARATA. L. ADEPS SUI SCROFÆ, _vulgo_ Axungia Porcina. E. ADEPS
SUILLUS PRÆPARATUS. D.
_Prepared Hog’s Lard. Fat. Axunge._[357]
QUALITIES. _Consistence_, soft or nearly semifluid. _Odour and Taste_,
none; at 97° it melts. CHEMICAL COMPOSITION. It consists of two distinct
bodies which appear to exist together in a state of mechanical mixture,
viz. _Stearin_, (from στεαρ tallow) which is white, brittle, and in
appearance somewhat resembling wax; and _Elain_ (from ελαὶον, oil) very
similar to vegetable oil in appearance, and is liquid at 59°. According
to the experiments of Braconnot, the proportion of _Elain_ is to that of
_Stearin_, in hog’s lard, as 62:38. SOLUBILITY. It is insoluble in water
and alcohol; with the alkalies it unites and forms soaps. INCOMPATIBLE
SUBSTANCES. _Extracts_, _Spirituous Preparations_, _Tinctures_, and
_Infusions_, are incapable of uniting perfectly with lard, without some
intermedium; the following substances on the contrary are capable of
contracting with it a most intimate union. 1. _All dry powders_, whether
of a vegetable or mineral nature. 2. _Fixed and Volatile Oils._ 3.
_Balsams._ 4. _Camphor._ 5. _Soaps._ It is principally employed in the
formation of ointments, plasters, and liniments.
ÆRUGO. L. D. (Sub-acetas Cupri _Impura._) SUB-ACETIS CUPRI. E.
_Verdigris._
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