Physiology: The Science of the BodyMartin, Ernest G.
Science
Physiology: The Science of the Body
Martin, Ernest G.
Physiology
A second thing to be mentioned about growth is a discovery which has
attracted a great deal of attention of late years; we will realize of
course that the chief thing in the making of new protoplasm is the
building together of protein out of amino acids. It is evident that for
the manufacture of new protein all the eighteen amino acids must be
present in sufficient proportion to give enough of each. There are some
plant proteins which lack one or two of the amino acids that are present
in human proteins and when a growing animal goes on a diet in which
these are the only proteins present it at once stops growing. Most of
the experiments proving this have been done on white rats, and it has
been found possible to keep a rat for more than a year at the size it
was when only a few weeks old simply by feeding it proteins in which one
or two amino acids were lacking. The fact that the animal lived during
this time proves that his protoplasmic wastage was made good and
therefore that there are proteins which can replace the body wastage but
cannot manufacture new protein. There is only one conclusion to be drawn
from this, namely that the daily wastage which the protein suffers does
not include all of it; some amino acids when once built in are there for
good; others, on the other hand, are constantly being lost in the
process of wastage, and these are the ones which must be replaced. There
is a common protein, gelatin, which is used a great deal for food, but
which by itself will not serve either for repair or growth because it
not only lacks some of the amino acids that are in living protoplasm,
but also some that are lost in the process of wastage. Gelatin is useful
as a food, therefore, only in combination with other proteins that
contain the necessary amino acids; or after the nitrogen has been taken
out, it becomes a good fuel.
One interesting question that was settled by the experiments described
above was whether the ability to grow is exclusively a matter of youth;
as we know, under ordinary conditions only young animals grow. When they
reach a certain age, they become mature and thereafter no increase in
size takes place. In the case of these white rats which were kept for
more than a year at the size of partially grown rats it was found that
as soon as their diet was changed to one in which all the necessary
amino acids were present they would begin at once to grow and grow to
full size, when they would stop growing just as they would have when
young. This proves that growth is not a matter of age, but is a matter
of achieving a certain size, and is controlled by factors which we do
not at present understand. An animal that has not been able to attain
[Illustration: Photo, Keystone View Co.
THE LUNCH HOUR IN A FRENCH SCHOOL WHERE EXERCISE, OUT-OF-DOOR LIFE,
SUNSHINE AND FRESH AIR ARE CONSIDERED ESSENTIAL]
[Illustration: Copyright, Paul Thompson
THE DIET KITCHEN ON A U. S. HOSPITAL SHIP]
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