Physiology: The Science of the BodyMartin, Ernest G.
Science
Physiology: The Science of the Body
Martin, Ernest G.
Physiology
chromatin material is not a simple lump in the nucleus. It looks rather
like a tiny string of beads thrown down carelessly, so as to become all
mixed together. Each bead is a single bit of chromatin, and these bits
are strung on a tiny thread. In an ordinary cell the beads are so mixed
together that no order can be distinguished among them, but if a cell
that is about to begin dividing is looked at it is found that the string
has straightened itself out, and also that it has broken into pieces.
The individual pieces are called _chromosomes_ and their number is
always the same for any one kind of animal or plant. There is a
parasitic worm whose cells have only four chromosomes, and the number
ranges from this up to as many as forty-eight in human beings. It may be
that other species have even more, but they become so hard to count when
there are as many as forty-eight that the number cannot be stated with
certainty. So far as can be judged, the number of chromosomes has little
to do with the complexity of the animal or plant, for some complex forms
have few chromosomes, and some simple forms many.
At the same time as the chromatin is breaking up into chromosomes two
tiny spots put in their appearance in the protoplasm of the cell on
opposite sides of the nucleus, and tiny threads extend from one spot to
the other through the nucleus. There are as many threads as there are
chromosomes, the whole group making up a spindle-shaped figure. The
chromosomes now become arranged at the middle of the spindle, and
apparently each chromosome becomes fastened to a thread. Next each
chromosome splits lengthwise through the middle and by what looks like a
shortening of the threads the split halves are pulled apart and drawn
to opposite tips of the spindle. The purpose of this elaborate scheme
seems to be to insure an exactly equal division of the chromosomes
between the cells, and the necessity of such an equal division will
become clear when we learn something of what the chromatin is for.
Meanwhile the description of cell division can be finished by saying
that after the halves of the chromosomes are pulled apart the whole mass
of protoplasm divides through the middle. As we stated above, sometimes
the cells thus produced are alike and sometimes they are different,
according to whether they are destined to become parts of similar or of
different structures. In either case the chromatin material that goes
into the two cells is exactly alike, so that if the cells themselves
become different there must have developed a difference in the
protoplasm at the two ends of the cell from which they came. Our bodies
are made up of millions of cells, of a great many different kinds, but
however different they may be the chromatin of each exactly duplicates
that of every other one, or did when the cells were first formed; there
is reason to believe that the chromatin may become changed during the
lifetime of the cells, at least in some cases.
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