We shall scarcely expect it to be as simple a matter to tell whether the tiny mass of protoplasm that we call a cell is alive or not as to decide whether a dog is dead or alive. For one thing, our most useful test of life, namely motion, cannot always be applied to single cells. We have in our bodies a great many cells, those in the brain, that we know are alive if any part of us is, but aside from the exceedingly gradual shifts in position that take place during growth the brain cells never make any motions at all, so far as anyone has ever been able to find out. Of course in the body of any ordinary animal most of the cells are hidden from view beneath the skin, but there are enough small transparent animals whose internal parts can be watched through the microscope to let us say with certainty that some of the cells which we know to be alive do not move. Tests of life that can be applied to all kinds of cells will necessarily be difficult to use, and we shall have to take the word of experts as to whether they have found particular cells alive or not, but the principle on which the tests are based is simple enough so that we can examine it. To do this, it will be necessary to turn our attention for a little while to some of the very tiniest of all living animals, those whose whole bodies consist of but one cell. When these tiny one-celled animals are watched through the microscope as they swim about it can be seen that in one important feature they behave just as we do ourselves; that is in their care not to neglect mealtime. To be sure, mealtime comes for them whenever they happen to hit against any tinier particle than themselves, which they can take in and digest. But for them, as for us, the taking of food from time to time is a necessity of life. Only a small part of the food thus taken in is added permanently to the bulk of the animal. In other words, the growth does not go on as fast as does the taking of food. Of course in ourselves, after we have reached full size, there is little or no increase in permanent bulk even though we do keep right on eating. Evidently in the tiny one-celled animal, and in us as well, food is constantly being used for something besides growth. It can be proved that this food is used for precisely the same purpose that gasoline is used in the automobile, namely to run the machine. In a very real sense every living thing is a machine, and will no more run without a supply of power than will any other machine. From the engineering standpoint animals can be classified along with automobiles and locomotives as “prime movers,” namely, as machines which develop their power within themselves. There are not many kinds of power which can be developed by prime movers. By far the commonest is that seen in locomotives and automobiles, namely the burning of some kind of fuel. We have always known that the locomotive operates by the burning of coal or oil in the fire box. A moment’s