Whilst yet a student, Mastai interested himself in an orphanage, which was founded by John Bonghi, a charitable mason of Rome. He spent in this institution the first seven years of his priesthood, devoting himself to the care of the orphans, who were, as yet, his only parishioners. The income which he derived from family resources was liberally applied in supplying the wants of these destitute children, and even in ministering to their recreation. It now became his duty to accompany, as a missionary priest, Monsignore Mazi, who was appointed Vicar-Apostolic for Chili, Peru and Mexico. These countries had thrown off the yoke of Spain and adopted Republican forms of government. The Vicar-Apostolic and his companions suffered much in the course of their voyage to America. They were cast into prison, at the Island of Majorca, by Spanish officials, who took it amiss that Rome should hold direct relations with the rebellious subjects of their government. Their ship was attacked by corsairs, and was afterwards in danger from a storm. A single circumstance only need be mentioned in order to show what the faithful ministers of the Church had to endure when traversing the inhospitable steppes of the Pampas. Once, at night, they had no other shelter than a wretched cabin built with the bones of animals, which still emitted a cadaverous odour. In those arid deserts, they suffered from thirst as well as from dearth of provisions. Great results can only be attained by equally great labors. If, after a period of privation, the travellers enjoyed no more luxurious refreshment than the waters of the crystal brook, it might well be said, “de torrente in viabibet propterea exaltabit caput.” (They shall be reduced to quench their thirst in the mountain stream, and therefore shall be exalted.) The delegates of the Holy Father were received with enthusiasm by the South American populations. Meanwhile, the narrow governments that were set over those countries raised so many difficulties that the mission was only partially successful. This mission, however, was not without benefit to the Reverend Count Mastai. It had been the means of developing the admirable qualities which he possessed. It had afforded him the opportunity of seeing many cities, as well as the manners and customs of many people. These lessons of travel were not addressed to an ordinary mind. His views were enlarged, elevated and refined by contact with so many rising or fallen civilizations, so many different nationalities, and by the spectacle of Nature, that admirable handmaid of the Divinity, with her varied splendors and her manifold wonders, astonishing no less in the immensity of the ocean than in the vast forests of the New World.