Transcriber's note: Text in italics is marked with _ underscore, text in small caps changed to ALL CAPS. Illustrations were moved to paragraph breaks. The index is sorted by page numbers within the alphabetical groups. This has been retained. Footnotes were moved to the end of the corresponding paragraph. A list of corrections made can be found at the end of the book. PLAGUE PLAGUE ITS CAUSE AND THE MANNER OF ITS EXTENSION--ITS MENACE--ITS CONTROL AND SUPPRESSION--ITS DIAGNOSIS AND TREATMENT BY THOMAS WRIGHT JACKSON, M.D. MEMBER AMERICAN RED CROSS SANITARY COMMISSION TO SERBIA, 1915; LATELY CAPTAIN AND ASSISTANT SURGEON, U. S. VOLUNTEERS; LATELY LECTURER ON TROPICAL DISEASES, JEFFERSON MEDICAL COLLEGE; MEMBER OF MANILA MEDICAL SOCIETY AND PHILIPPINE ISLANDS MEDICAL ASSOCIATION; AUTHOR OF A TEXT BOOK ON TROPICAL MEDICINE; DIRECTOR, DEPARTMENT OF SANITATION AND EPIDEMIOLOGY FOR H. K. MULFORD COMPANY WITH BACTERIOLOGIC OBSERVATIONS BY DR. OTTO SCHÖBL BUREAU OF SCIENCE, MANILA _ILLUSTRATED_ PRESS OF J. B. LIPPINCOTT COMPANY COPYRIGHT, 1916 BY THOMAS WRIGHT JACKSON, M.D. THIS BOOK IS DEDICATED BY THE AUTHOR TO DR. ALDO CASTELLANI REGIUS PROFESSOR OF TROPICAL DISEASES, UNIVERSITY OF NAPLES. EMINENT IN MEDICAL RESEARCH, MY FRIEND, COLLEAGUE AND COMRADE DURING STRENUOUS DAYS IN SERBIA. CONTENTS PAGE INTRODUCTION 11 CHAPTER I ITS HISTORY AND ITS EXTENSION 19 History of Plague--The Widespread Dissemination of Plague in Recent Years--The Appearance of Plague in Porto Rico, New Orleans and Manila. CHAPTER II THE CAUSE AND THE MENACE OF PLAGUE 28 Causation of the Disease and its Mode of Conveyance--Types of Plague--Chronic Plague and Immunity in Rats--Flea Conveyance of Plague Bacilli--The Stability of Virulence of Plague Bacilli--Summary of Facts Concerning the Cause and Manner of Extension of Plague. CHAPTER III ITS CONTROL AND SUPPRESSION 40