Plague: Its Cause and the Manner of its Extension, Its Menace, Its Control and Suppression, Its Diagnosis and TreatmentJackson, Thomas Wright
History
Plague: Its Cause and the Manner of its Extension, Its Menace, Its Control and Suppression, Its Diagnosis and Treatment
Jackson, Thomas Wright
Plague; Rats as carriers of disease
THE CERVICAL BUBO.--The enlarged lymphatic gland was
surrounded with a thickened capsule. Necrosis existed in the
subcapsular part of the gland, where it formed an almost
continuous circular zone, leaving the central part less
changed. Smaller irregular necrotic foci were scattered
throughout the section. Polymorphonuclears in various stages
of disintegration were found throughout the section.
_The Lungs._--Very few blood extravasations were present in
the alveoli; otherwise normal.
_The Spleen._--The capsule was thin. There were subcapsular
hemorrhages. The Malpighian bodies were somewhat enlarged,
but of normal structure. Throughout the parenchyma irregular
multiple necrotic foci were found, leaving but little of
spleen tissue intact. Numerous polymorphonuclears which were
present showed varying degrees of karyorrhexis.
_The Kidneys._--The outline of the cells was indefinite; a
few miliary hemorrhages existed in the cortical part of the
organ.
_The Liver._--There was excessive congestion, fatty
degeneration, and pigmentation of the cells. The capsule was
slightly thickened.
_The Skin._--The epithelium was missing in one place in the
section, and cellular infiltration extended from that place
into the subepithelial layer of the surrounding skin. The
same kind of infiltration reached deep into the skin, stripes
of cellular infiltration penetrating into the tissue along
the muscle fibres. There was no direct connection between the
cellular infiltration and the follicles of the hair.
It may be well to describe in detail the time of death from
plague among these and the other animals in this outbreak, as
well as the time when the plague house was disinfected.
The first animal (rat 1) having been inoculated on August 27,
in the afternoon, died of plague within three days (August
30). The second animal (rat 2) died twenty-four hours later.
Guinea-pigs 3, 4, and 5 (see plan) were found dead on the
morning of September 2; that is, two days after the death of
rat 2 and three days after the death of rat 1.
The same day that the three guinea-pigs were found dead of
plague, rooms I, III, IV, and VI were thoroughly disinfected.
The floor, the ceiling, and the walls were sprayed with
kerosene and lysol solution. The remaining animals in room VI
were destroyed, and the cages disinfected. No animals were
kept in rooms I, III, and IV at that time.
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