_China._--Since January 1, 1911, plague was reported in varying intensity in (provinces and towns) Manchuria, Peking, Tien-tsin, Chefo, Shantung, Shanghai, Amoy, Foochow, Swatow, Canton, Pakhoi and Laichow. _Indo-China._--At Saigon, in March and April, 1911, many cases reported. April 17 to May 7, 56 cases; 17 deaths. May 22 to May 28, 37 cases; 12 deaths. _Siam._--In Bangkok plague was more severe during 1911 than in any previous year. March 15 to April 15, 33 cases and 29 deaths. _Java and Sumatra._--In Java, May 25 to June 3, 105 cases and 62 deaths (one province). In Sumatra plague was present, no statistics. _Straits Settlements._--A few cases, mostly imported, reported in 1911. _Japan._--A few cases at Kobe in 1911. In Formosa, from April 2 to April 15, 31 cases; 24 deaths. _Egypt._--Plague reported from Port Said, Suakin (on board ship), Cairo and Alexandria; also from 11 provinces. The province of Kena had a severe outbreak, May 5 to May 31, 51 cases and 49 deaths. _Persia._--Several cases reported from ports on the Persian Gulf. _Turkey in Asia._--A few cases at Muscat, Basra and at Port of Jeddah. _British East Africa._--Kismayu and Port Florence reported a few cases in April, 1911. _Mauritius._--January 1 to April 11, 110 cases and 70 deaths. _Portuguese East Africa._--Plague was reported present at Nahoria in May, 1911. _Russia._--In the Kirgis Steppe in the Astrakan Government in January, 50 cases; 30 deaths. _South America._--Plague prevailed during 1911 in Peru, Ecuador, Brazil, Chile and Venezuela. No severe outbreak except in Peru, where from February to May many cases occurred and died. At Libertad, in March, were reported 60 cases and 23 deaths. APPEARANCE OF PLAGUE IN PORTO RICO, NEW ORLEANS AND MANILA.--The developments of 1912, which most concern us, were the appearance of human plague and the discovery of plague-infected rats in Porto Rico, Cuba, and the Philippines, and the discovery of infected rats in New Orleans. Thus the Atlantic cities of the United States were for the first time seriously threatened, and the menace of the pestilence at home loomed up on our horizon with sufficient prominence to excite public concern. Our protectors and guardians of the United States Public Health Service, to whose watchfulness we must credit our prolonged escape from the plague, are carrying out all the protective measures at their command with the utmost activity. At the present time we find Porto Rico freed from the disease. New Orleans has undergone and is still undergoing treatment which may be expected, most confidently, to clear it of both human and animal plague.