Every possible remedy was used to check the terrible disease which was preying upon the unfortunate boys, but in vain. At times the symptoms would be somewhat mitigated, and the most sanguine hopes of the fond, watching mother would be excited, but in vain. The improvement always proved to be but temporary, and the poor sufferers would speedily relapse into the same dreadful condition again, and gradually grew worse. At last, the poor mother was obliged to give up all hope, in utter despair watching the daily advances of the awful malady which inch by inch destroyed the life, the humanity, the very mind and soul of her once promising sons. Sadly she took them back to her Western home, there to see them suffer, perhaps for years before death should kindly release them, the terrible penalty of sin committed almost before they had arrived at years of responsibility. How these mere infants learned the vice we were never able to determine. We have no doubt that opportunities sufficient were presented them, as the parents seemed to have very little appreciation of danger from this source. Had greater vigilance been exercised, we doubt not that the discovery of the vice at the beginning would have resulted in the salvation of these two beautiful boys, who were sacrificed upon the altar of concupiscence. Two or three years after we first saw the cases, we heard from them, and though still alive, their condition was almost too horrible for description. Three or four similar cases have come to our knowledge. Boys, are you guilty? Think of the fearful fate of these boys, once as joyous and healthy as you. When you are tempted to sin, think of the fearful picture of the effects of sin which they present. Have you ever once dared to commit this awful sin? Stop, never dare to do the thing again. Take a solemn vow before God to be pure. Your fate may be as sad, your punishment as terrible. No one can tell what the results may be. Absolute purity is the only safe course.