Animals may also be poisoned by certain toxic seeds (_e.g._ corn cockle) fed to them with cereal grains, in feeding stuffs generally, or in the refuse seeds from the sources mentioned. Here again judgment is necessary, and it is probably advisable on all counts to burn the weed seeds and similar refuse from the sources mentioned. Poisonous seeds may occur in low quality feeding stuffs, and poisonous seeds of foreign origin are occasionally sold for food purposes owing to the mistaken idea that they are a valuable addition to the ration (_e.g._ the poisonous “Java” beans). In any case in which an animal is believed to have been poisoned purchased feeding stuffs should always be considered as a possible source of injury and be submitted to examination. Clippings and trimmings from gardens and shrubberies have proved a more or less common cause of live stock poisoning, such material being too often carelessly thrown out for animals to pick over. In such circumstances it may quite easily happen that the animals get yew, daphne, privet, rhododendron, azalea, solanums, and other plants of a poisonous character. For this reason it is better to destroy such trimmings, etc., by burning them, or by adding them to the compost heap as the case may be. A further source of poisoning must be noted here—fleshy and parasitic fungi (toadstools, rust fungi), moulds and similar organisms. Many toadstools are directly poisonous when eaten, but the microscopic organisms are probably in themselves harmless, though taken with food which they are responsible for injuring (bad hay, cakes, etc.), the poisoning being due to the changed and damaged feeding stuffs, or possibly to poisonous principles directly elaborated by the microscopic fungi. Fungi and related organisms cannot be dealt with in this volume, but it may at least be said that the use of mouldy hay and similarly affected feeding stuffs is attended with some danger, which is not yet very clearly defined. =Effect of Soil, Climate and Cultivation on the Toxic Properties of Plants.= In general, wild poisonous plants are richer in either alkaloids or glucosides than the same species when cultivated, though there are exceptions. In many cases it is found that plants vary considerably in toxicity, or the percentage content of the poisonous principle, according to soil, light, moisture, etc. Solanaceous plants in particular vary in this way, and one or two instances may be given as examples. _Solanum nigrum_ varies so much that it has been regarded as harmless in one country and quite poisonous in another (p. 52).