For the temperature quinin is the best agent. In milder cases it can be given in tonic doses, associated with antifebrin, with or without morphin, to quiet the patient. In severe forms quinin must be pushed, giving as much as twenty grains at a dose, to be repeated as necessary. A saline purge, magnesium sulphate in full doses, is useful to eliminate the ptomains. The strength of the patient must be supported by the free use of stimulants and frequent small quantities of nutritious food. Milk with whisky is excellent. Peptonoids and beef juice are given several times in the day. Favorable symptoms are heralded by the lowering of the temperature, the abatement of toxic symptoms, the reduction of the edema, and the deep redness, as well as the softening of the hard and painful edematous walls of the wound, followed by the breaking down of more or less tissue with the production of pus. GANGRENE Gangrene in these cases is often due to undue bruising or pressure on the parts during operation, and otherwise to the tension of sutures. It is best to allow the gangrenous mass to remain, keeping it aseptic by antiseptic measures, as it is often found that only the superficial layer and the edge or edges of the wound have suffered. As demarcation is well established the gangrenous portions may be removed with the dressing or small seizing forceps. _Walcher’s_ pattern of a dressing forceps is shown in Fig. 25, a toothed seizing forceps being represented in Fig. 26. [Illustration: FIG. 25.—WALCHER DRESSING FORCEPS.] [Illustration: FIG. 26.—TOOTHED SEIZING FORCEPS.] The wound from now on may be at first subjected to a rather strong aqueous solution of hydrogen peroxid, fifty per cent, followed by the same sublimate solution used throughout. Iodoform gauze dressing, with or without dusting of iodoform or iodol, is continued with the purpose of draining the pus secretion thrown off by the granulating tissue which soon begins to fill the wound, as well as to exert its antiseptic and stimulating influence upon the granulations. Lazy or glassy granulations are removed with the curette as they appear, or a cauterant, in the form of a nitrate-of-silver stick. Gradually the new tissue contracts, the epidermal edges begin to fold over the surface. Dry dressing, in the form of aristol or boric acid, may then be used, to produce ultimate healing under an aseptic scab, or lint moistened with two-per-cent salicylic oil or boric vaselin is placed upon the wound. A formula of the latter is made up as follows: Boric acid 3 parts Vaselin 5 ” Paraffin 10 ” A desirable boric-acid oil for the same purpose is composed of: Boric acid 3 parts Cera alba 4 ” Ol. oliva 20 ” The latter must be changed daily until cicatrization has been established.