Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and ExpertsBlyth, Alexander Wynter
Science
Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and Experts
Blyth, Alexander Wynter
Poisons
The stomach was found small, contracted, with many adhesions to the
pancreas and liver; it was about 12 centimetres long (4·7 inches), and
from 2 to 2·5 centimetres (·7 to ·9 inch) broad, contracted to somewhat
the form of a cat’s intestine; there were several transverse rugæ; the
walls were thickened at the small curvature, measurements giving 5 mm.
(·19 inch) in the middle, and beyond about 2·75 mm. (·11 inch); in the
upper two-thirds the lumen was so contracted as scarcely to admit the
point of the little finger. The inner surface was covered with a layer
of pus, with no trace of mucous tissue, and was everywhere pale red,
uneven, and crossed by cicatricial bands. In two parts, at the greater
curvature, the mucous surface was strongly injected in a ring-like form,
and in the middle of the ring was a deep funnel-shaped ulcer; a part of
the rest of the stomach was strongly injected and scattered over with
numerous punctiform, small, transparent bladders. The gullet was
contracted at the upper part (just below the epiglottis) from 20 to 22
mm. (·78 to ·86 inch) in diameter; it then gradually widened to measure
about 12 mm. (·47 inch) at the diaphragm; in the neighbourhood of the
last contraction the tissue was scarred, injected, and ulcerated; there
were also small abscesses opening into this portion of the gullet.
E. Fraenkel and F. Reiche[74] have studied the effects of sulphuric acid
on the kidney. In rapid cases they find a wide-spread coagulation of the
epithelium in the convoluted and straight urinary canaliculi, with
destruction of the kidney parenchyma, but no inflammation.
[74] Virchow’s _Archiv_, Bd. 131, f. 130.
§ 62. The museums of the different London hospitals afford excellent
material for the study of the effects of sulphuric acid on the pharynx,
gullet, and stomach; and it may be a matter of convenience to students
if the more typical examples at these different museums be noticed in
detail, so that the preparations themselves may be referred to.
_In St. Bartholomew’s Museum_, No. 1942, is an example of excessive
destruction of the stomach by sulphuric acid. The stomach is much
contracted, and has a large aperture with ragged edges; the mucous
membrane is thickened, charred, and blackened.
No. 1941, in the same museum, is the stomach of a person who died
from a large dose of sulphuric acid. When recent, it is described as
of a deep red colour, mottled with black; appearances which, from
long soaking in spirit, are not true at the present time; but the
rough, shaggy state of the mucous tissue can be traced; the gullet
and the pylorus appear the least affected.
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