Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and ExpertsBlyth, Alexander Wynter
Science
Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and Experts
Blyth, Alexander Wynter
Poisons
When an aqueous solution of carbolic acid is shaken up with ether,
benzene, carbon disulphide, or chloroform, it is fully dissolved by the
solvent, and is thus easily separated from most solutions in which it
exists in the free state. Petroleum ether, on the other hand, only
slightly dissolves it in the cold, more on warming. Carbolic acid mixes
in all proportions with glycerin, glacial or acetic acid, and alcohol.
It coagulates albumen, the precipitate being soluble in an excess of
albumen; it also dissolves iodine, without changing its properties. It
dissolves many resins, and also sulphur, but, on boiling, sulphuretted
hydrogen is disengaged. Indigo blue is soluble in hot carbolic acid, and
may be obtained in crystals on cooling. Carbolic acid is contained in
castoreum, a secretion derived from the beaver, but it has not yet been
detected in the vegetable kingdom. The source of carbolic acid is at
present coal-tar, from which it is obtained by a process of
distillation. There are, however, a variety of chemical actions in the
course of which carbolic acid is formed.
§ 217. The common disinfecting carbolic acid is a dark reddish liquid,
with a very strong odour; at present there is very little phenol in it;
it is mainly composed of meta- and para-cresol. It is officinal in
Germany, and there must contain at least 50 per cent. of the pure
carbolic acid. The pure crystallised carbolic acid is officinal in our
own and all the continental pharmacopœias. In the British Pharmacopœia,
a solution of carbolic acid in glycerin is officinal; the proportions
are 1 part of carbolic acid and 4 parts of glycerin, that is, strength
by measure = 20 per cent. The Pharmacopœia Germanica has a _liquor natri
carbolici_, made with 5 parts carbolic acid, 1 caustic soda, and 4 of
water; strength in carbolic acid = 50 per cent. There is also a strongly
alkaline crude sodic carbolate in use as a preservative of wood.
There are various disinfecting fluids containing amounts of carbolic
acid, from 10 per cent. upwards. Many of these are somewhat complex
mixtures, but, as a rule, any poisonous properties they possess are
mainly due to their content of phenol or cresol. A great variety of
disinfecting powders, under various names, are also in commerce,
deriving their activity from carbolic acid. Macdougall’s disinfecting
powder is made by adding a certain proportion of impure carbolic acid to
a calcic sulphite, which is prepared by passing sulphur dioxide over
ignited limestone.
=Calvert’s carbolic acid powder= is made by adding carbolic acid to the
siliceous residue obtained from the manufacture of aluminic sulphate
from shale. There are also various carbolates which, by heating or
decomposing with sulphuric acid, give off carbolic acid.
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