Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and ExpertsBlyth, Alexander Wynter
Science
Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and Experts
Blyth, Alexander Wynter
Poisons
=Commercial cresol= is at ordinary temperatures a liquid, and cannot be
obtained in a crystalline state by freezing. Its boiling-point is from
198° to 203°; it is almost insoluble in strong ammonia, and, when 16
volumes are added, it then forms crystalline scales. On the other hand,
carbolic acid is soluble in an equal volume of ammonia, and is then
precipitated by the addition of 1½ volume of water. Cresol is insoluble
in small quantities of pure 6 per cent. soda solution; with a large
excess, it forms crystalline scales; while carbolic acid is freely
soluble in small or large quantities of alkaline solutions.
Cold petroleum spirit dissolves cresol, but no crystalline scales can be
separated out by a freezing mixture. Carbolic acid, on the contrary, is
but sparingly soluble in cold petroleum, and a solution of carbolic acid
in hot petroleum, when exposed to sudden cold produced by a freezing
mixture, separates out crystals from the upper layer of liquid. Cresol
is miscible with glycerin of specific gravity 1·258 in all proportions;
1 measure of glycerin mixed with 1 measure of cresol is completely
precipitated by 1 measure of water. Carbolic acid, under the same
circumstances, is not precipitated. The density of cresol is about
1·044. It forms with bromine a tri-bromo-cresol, but this is liquid at
ordinary temperatures, while tri-bromo-phenol is solid. On the other
hand, it resembles carbolic acid in its reactions with ferric chloride
and with nitric and sulphuric acid.
§ 233. =Creasote= or =Kreozote= is a term applied to the mixture of
crude phenols obtained from the distillation of wood-tar. It
consists of a mixture of substances of which the chief are guaiacol
or oxycresol (C₇H₈O₂), boiling at 200°, and creasol (C₈H₁₀O₂),
boiling at 217°; also in small quantities phlorol (C₈H₁₀O), methyl
creasol (C₉H₁₂O₂), and other bodies. Morson’s English creasote is
prepared from Stockholm tar, and boils at about 217°, consisting
chiefly of creasol; it is not easy, by mere chemical tests, to
distinguish creasote from cresylic acid. Creasote, in its reactions
with sulphuric and nitric acid, bromine and gelatin, is similar to
carbolic and cresylic acids, and its solubility in most solvents is
also similar. It is, however, distinguished from the tar acids by
its insolubility in Price’s glycerin, specific gravity 1·258,
whether 1, 2, or 3 volumes of glycerin be employed. But the best
test is its action on an ethereal solution of nitro-cellulose.
Creasote mixes freely with the B.P. collodium, while cresylic acid
or carbolic acid at once coagulates the latter. With complicated
mixtures containing carbolic acid, cresol, and creasote, the only
method of applying these tests with advantage is to submit the
mixture to fractional distillation.
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