But time has changed all that, and already the triumphs
of democracy have been as signal in biology as they have been in
politics, and far more rapid. The sturdy little citizen-cells have
steadily but surely fought their way to recognition as the controlling
power of the entire body-politic, have forced the ganglion-oligarchy to
admit that they are but delegates, and even the tyrant mind to concede
that he rules by their sufferance alone. His power is mainly a veto, and
even that may be overruled by the usual two-thirds vote.
In fact, if we dared to presume to criticise this magnificent theory of
disease, we would simply say that it is not "cellular" enough, that it
hardly as yet sufficiently recognizes the individuality, the
independence, the power of initiative, of the single constituent cell.
It is still a little too apt to assume, because a cell has donned a
uniform and fallen into line with thousands of its fellows to form a
tissue in most respects of somewhat lower rank than that originally
possessed by it in its free condition, that it has therefore surrendered
all of its rights and become a mere thing, a lever or a cog in the great
machine. Nothing could be further from the truth, and I firmly believe
that our clearest insight into and firmest grasp upon the problems of
pathology will come from a recognition of the fact that, no matter how
stereotyped, or toil-worn, or even degraded, the individual cells of any
tissue may have become, they still retain most of the rights and
privileges which they originally possessed in their free and untrammeled
am[oe]boid stage, just as in the industrial community of the world about
us. And, although their industry in behalf of and devotion to the
welfare of the entire organism is ever to be relied upon, and almost
pathetic in its intensity, yet it has its limits, and when these have
been transgressed they are as ready to "fight for their own hand,"
regardless of previous conventional allegiance, as ever were any of
their ancestors on seashore or rivulet-marge. And such rebellions are
our most terrible disease-processes, cancer and sarcoma. More than this:
while, perhaps, in the majority of cases the cell does yeoman service
for the benefit of the body, in consideration of the rations and fuel
issued to it by the latter, yet in many cases we have the curious, and
at first sight almost humiliating, position of the cell absorbing and
digesting whatever is brought to it, and only turning over the surplus
or waste to the body. It would almost seem as if our lordly _Ego_ was
living upon the waste-products, or leavings, of the cells lining its
food-tube.
Public-domain text, read in full here on John Shaqi.
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