Besides tuberculosis of the cerebral membranes with which children are afflicted, _tuberculosis of the brain_ may occur, although this disease is very rare. Tuberculosis of the brain appears in the shape of small tumors in all parts of the brain. After longer duration of tuberculosis of the brain, tubercular meningitis appears. The process of this disease may be varied. In some cases the development of cerebral tuberculosis is manifested by the sudden appearance of high fever temperatures or violent headache; to this may be added, slackening of the pulse, vomiting, stiff neck and isolated cases of palsy; sometimes an attack of convulsions is the first manifestation. In other cases the beginning can not be accurately determined, as the beginning symptoms of the disease are so slight as to escape notice. Impaired process of nutrition, languor and headache are symptoms from which the existence of some serious affliction may be inferred without being able to determine its nature in the earlier stages. Again in other cases the disease may proceed through all its stages without any cerebral appearances whatever. This is especially true of small tubercles and of diseases of infants. However, we more frequently observe in children than in adults convulsions of varied intensity and distribution. Nutrition is more and more impaired as the disease progresses, in isolated cases only, a temporary improvement may be observed. The _end_ of cerebral tuberculosis has been _death_ before this. Ten days to two weeks, even three weeks may pass from the first appearance of tubercular meningitis to the completion of the process of the disease, attended by feverish motions characteristic of this condition and by cerebral symptoms, first with the character of excitement, later on with that of palsy. The treatment of cerebral tuberculosis has been entirely insufficient before this. Let us hope that it will be possible to effect a cure by means of Koch's new method. _Tuberculosis of the Kidneys_ is met with from the earliest childhood till old age. Most frequently the male sex is afflicted during manhood. In most cases tuberculosis also exists in other organs, especially in the urinary and sexual apparatus. The existence of pulmonary or intestinal tuberculosis is not essential. The symptoms of renal tuberculosis are of such general and indefinite character, that it is often impossible to fully determine the disease. Now, however, it will be more easily possible on account of Koch's discovery. The _urine_ may, but need not contain pus and blood. Sometimes small lumps are found in the urine. _Pains_ are only sometimes felt in the renal regions; _fever_ may be occasionally attendant. The disease lasts for months and years; though before now it has inevitably resulted in death, though it has in exceptional cases taken ten years or more.