There are lots of nerve cells, billions of them. That ought to be plenty, and yet--well, perhaps sometimes they are not well developed, or their synapses are not close enough to make good connections. [Illustration: Fig. 8.--A two-neurone reflex arc. (Figure text: stimulus, skin, sensory axon, bit of the spinal cord, motor axon, muscle)] Examined under the microscope, the nerve cell is seen to contain, besides the "nucleus" which is present in every living cell and is essential for maintaining its vitality and special characteristics, certain peculiar granules which appear to be stores of fuel to be consumed in the activity of the cell, and numerous very fine fibrils coursing through the cell and out into the axon and dendrites. The _reflex arc can now be described_ more precisely than before. Beginning in a sense organ, it extends along a sensory axon (really along a team of axons acting side by side) to its end-brush in a lower center, where it crosses a synapse and enters the dendrites of a motor neurone and so {37} reaches the cell body and axon of this neurone, which last extends out to the muscle (or gland). The simplest reflex arc consists then of a sensory neurone and a motor neurone, meeting at a synapse in a lower or reflex center. This would be a two-neurone arc. [Illustration: Fig. 9.--A three-neurone arc, concerned in respiration. This also illustrates how one nerve center influences another. (Figure text: white matter, gray matter, lung, respiratory center in the brain stem, diaphragm, motor center in cord for the diaphragm)] Very often, and possibly always, the reflex arc really consists of three neurones, a "central" neurone intervening between the sensory and motor neurones and being connected through synapses with each. The central neurone plays an important rôle in coördination. COÖRDINATION The internal structure of nerve centers helps us see how coördinated movement is produced. The question is, how {38} several muscles are made to work together harmoniously, and also how it is possible that a pin prick, directly affecting just a few sensory axons, causes a big movement of many muscles. Well, we find the sensory axon, as it enters the cord, sending off a number of side branches, each of which terminates in an end-brush in synaptic connection with the dendrites of a motor nerve cell. [Illustration: Fig. 10.--Coördination brought about by the branching of a sensory axon. (Figure text: cord, sensory neurone, motor neurone)] Thus the nerve current from a single sensory neurone is distributed to quite a number of motor neurones. Where there are central neurones in the arc, their branching axons aid in distributing the excitation; and so we get a big movement in response to a minute, though intense stimulus.