=Nerve-endings in the Skin.=--"Many of the afferent skin-nerves end in connection with hair-bulbs; the fine hairs over most of the cutaneous surface, projecting from the skin, transmit any movement impressed on them, with increased force, to the nerve-fibres at their fixed ends. Fine branches of axis-cylinders have also been described as penetrating between epidermic cells and ending there without terminal organs. In or immediately beneath the skin several peculiar forms of nerve end-organs have also been described; they are known as (1) _Touch-cells_; (2) _Pacinian corpuscles_; (3) _Tactile corpuscles_; (4) _End-bulbs_."[23] [Illustration: FIG. 24.--End-bulbs from the conjunctiva of the human eye, magnified. ] These bodies all consist essentially of granules formed of connective tissue, in which or round about which one or more sensory nerve-fibres terminate. They probably magnify impressions just as a grain of sand does in a shoe, or a crumb does in a finger of a glove. =Touch, or the Pressure Sense.=--"Through the skin we get several kinds of sensation; touch proper, heat and cold, and pain; and we can with more or less accuracy localize them on the surface of the body. The interior of the mouth possesses also three sensibilities. Through touch proper we recognize pressure or traction exerted on the skin, and the force of the pressure; the softness or hardness, roughness or smoothness, of the body producing it; and the form of this when not too large to be felt all over. When to learn the form of an object we move the hand over it, muscular sensations are combined with proper tactile, and such a combination of the two sensations is frequent; moreover, we rarely touch anything without at the same time getting temperature sensations; therefore pure tactile feelings are rare. From an evolution point of view, touch is probably the first distinctly differentiated sensation, and this primary position it still largely holds in our mental life."[24] Objects are most important to us when in direct contact. The chief function of our eyes and ears is to enable us to prepare ourselves for contact with approaching bodies, or to ward such contact off. They have accordingly been characterized as organs of anticipatory touch. "The delicacy of the tactile sense varies on different parts of the skin; it is greatest on the forehead, temples, and back of the forearm, where a weight of 2 milligr. pressing on an area of 9 sq. millim. can be felt. "In order that the sense of touch may be excited neighboring skin-areas must be differently pressed. When the hand is immersed in a liquid, as mercury, which fits into all its inequalities and presses with practically the same weight on all neighboring immersed areas, the sense of pressure is only felt at a line along the surface, where the immersed and non-immersed parts of the skin meet.