Keeps the blood cool and regulates the stomach. Persons subject to headache can insure themselves freedom from this malady by drinking it liberally in the morning before breakfast. Sold by JOHN F. HENRY, at the U.S. Family Medical Depot, 8 College Place, New-York. * * * * * PRANG'S CHROMOS are celebrated for their close resemblance to oil paintings. Sold in all Art Stores throughout the world. PRANG'S LATEST CHROMOS: "Four Seasons," by J. M. Hart. Illustrated catalogues sent free on receipt of stamp by L. PRANG & CO., Boston. * * * * * PUNCHINELLO. With a large and varied experience in the management and publication of a paper of the class herewith submitted, and with the still more positive advantage of an Ample Capital to justify the undertaking, the PUNCHINELLO PUBLISHING CO. OF THE CITY OF NEW YORK. Presents to the public for approval, the new ILLUSTRATED HUMOROUS AND SATIRICAL WEEKLY PAPER. PUNCHINELLO, The first number of which was issue under date of Apr 2. PUNCHINELLO will be entirely original; humourous and witty without vulgarity, and a satirical without malice. It will be printed on a superior tinted paper of sixteen pages size 13 by 9, and will be for sale by all respectable news-dealers who have the judgment to know a good thing when they see it, or by subscription from this office. ORIGINAL ARTICLES, Suitable for the paper, and Original Designs, or suggestive ideas or sketches for illustrations, upon the topics of the day, are always acceptable and will be paid for liberally. Rejected communications cannot be returned, unless postage stamps are inclosed. TERMS: One copy, per year, in advance $4 00 Single copies 10 A specimen copy will be mailed free upon the receipt of ten cents. One copy, with the Riverside Magazine, or any other magazine or paper, price $2.50, for 5 50 One copy, with any magazine or paper, price, $4, for 7 00 All communications, remittances, etc., to be addressed to PUNCHINELLO PUBLISHING CO., No. 83 Nassau Street, P.O. Box, 27383, NEW YORK * * * * * THE MYSTERY OF MR. E. DROOD. The New Burlesque Serial, Written expressly for PUNCHINELLO, By ORPHEUS C. KERR, Commenced in this number, will be continued weekly throughout the year. A sketch of the eminent author, written by his bosom friend, with superb illustrations of 1ST. THE AUTHOR'S PALATIAL RESIDENCE AT BEGAD'S HILL, TICKNOR'S FIELDS, NEW JERSEY. 2D. THE AUTHOR AT THE DOOR OF SAID PALATIAL RESIDENCE, taken as he appears "Every Saturday." will also be found in this number. Single Copies, FOR SALE BY ALL NEWSMEN, (OR MAILED FROM THIS OFFICE, FREE,) Ten Cents. Subscription for One Year, one copy, with $2 Chromo Premium, $4.