The philosophic empiricism initiated by Locke was thus disintegrative in intent. It optimistically took it for granted that when the burden of blind custom, imposed authority, and accidental associations was removed, progress in science and social organization would spontaneously take place. Its part was to help in removing the burden. The best way to liberate men from the burden was through a natural history of the origin and growth in the mind of the ideas connected with objectionable beliefs and customs. Santayana justly calls the psychology of this school a malicious psychology. It tended to identify the history of the formation of certain ideas with an account of the things to which the ideas refer--an identification which naturally had an unfavorable effect on the things. But Mr. Santayana neglects to notice the social zeal and aim latent in the malice. He fails to point out that this "malice" was aimed at institutions and traditions which had lost their usefulness; he fails to point out that to a large extent it was true of them that an account of their psychological origin was equivalent to a destructive account of the things themselves. But after Hume with debonair clarity pointed out that the analysis of beliefs into sensations and associations left "natural" ideas and institutions in the same position in which the reformers had placed "artificial" ones, the situation changed. The rationalists employed the logic of sensationalistic-empiricism to show that experience, giving only a heap of chaotic and isolated particulars, is as fatal to science and to moral laws and obligations as to obnoxious institutions; and concluded that "Reason" must be resorted to if experience was to be furnished with any binding and connecting principles. The new rationalistic idealism of Kant and his successors seemed to be necessitated by the totally destructive results of the new empirical philosophy. Two things have rendered possible a new conception of experience and a new conception of the relation of reason to experience, or, more accurately, of the place of reason _in_ experience. The primary factor is the change that has taken place in the actual nature of experience, its contents and methods, as it is actually lived. The other is the development of a psychology based upon biology which makes possible a new scientific formulation of the nature of experience.