The first specimen was in a good state of preservation on its arrival. I never saw a more beautiful or robust proliferation epitherial cell nest in my life. It must have been secured immediately after the old epitherial had left the nest, and it was in good order on its arrival. The whole lobule was looking first-rate. You might ride for a week and not run across a prettier lobule or a more artistic aggregation of cell nests outside a penitentiary. Only one cell nest had been allowed to dry up on the way, and this looked a good deal fatigued. In one specimen I noticed a carneous degeneration, but this is really no reflection on Mr. Flannery personally. While he has been ill it is not surprising that he should allow his cell nests to carneously degenerate. Such a thing might happen to almost any of us. One of the scrapings from the sore on the right posterior fauces, I found on its arrival, had been seriously injured, and therefore not available. I return it herewith. From an examination, which has been conducted with great care, I am led to believe that the right posterior rafter of Mr. Flannery's mouth is slightly indurated, and it is barely possible that the northeast duplex and parotid gable end of the roof of his mouth may become involved. I wish you would ask Mr. Flannery's immediate relatives, if you can do so without arousing alarm in the breast of the patient, if there has ever been a marked predisposition on the part of his ancestors to tubercular gumboil. I do not wish to be understood as giving this diagnosis as final at all, but from what I have already stated, taken together with other clinical and pathological data within my reach, and the fact that minute, tabulated gumboil bactinae were found floating through some of the cell nests, I have every reason to fear the worst. I would be glad to receive from you for microscopic examination a fragment of Mr. Flannery's malpighian layer, showing evidences of cell proliferation. I only suggest this, of course, as practicable in case there should be a malpighian layer which Mr. Flannery is not using. Do not ask him to take a malpighian layer off her cell nest just to please me. From one microscopic examination I hardly feel justified in giving a diagnosis, nor care to venture any suggestion as to treatment, but it might be well to kalsomine the roof of Mr. Flannery's mouth with gum-arabic, white lime and glue in equal parts.