Of all the republics which had conferred luster upon Italy in its mediaeval period of prosperity Venice alone remained independent. She never submitted to a tyrant; and her government, though growing yearly more closely oligarchical, was acknowledged to be just and liberal. During the centuries of her greatest power Venice hardly ranked among Italian States. It had been her policy to confine herself to the lagoons and to the extension of her dominion over the Levant. In the fifteenth century, however, this policy was abandoned. Venice first possessed herself of Padua, by exterminating the despotic House of Carrara; next of Verona, by destroying the Scala dynasty. Subsequently, during the long dogeship of Francesco Foscari (1423-1457), she devoted herself in good earnest to the acquisition of territory upon the mainland. Then she entered as a Power of the first magnitude into the system of purely Italian politics. The Republic of S. Mark owned the sea coast of the Adriatic from Aquileia to the mouths of the Po; and her Lombard dependencies stretched as far as Bergamo westward. Her Italian neighbors were, therefore, the Duchy of Milan, the little Marquisate of Mantua, and the Duchy of Ferrara. When Constantinople fell in 1453, Venice was still more tempted to pursue this new policy of Italian aggrandizement. Meanwhile her growing empire seemed to menace the independence of less wealthy neighbors. The jealousy thus created and the cupidity which brought her into collision with Julius II. in 1508, exposed Venice to the crushing blow inflicted on her power by the combined forces of Europe in the war of the League of Cambray. From this blow, as well as from the simultaneous decline of their Oriental and Levantine commerce, the Venetians never recovered.