Reports of Trials for Murder by Poisoning;: by Prussic Acid, Strychnia, Antimony, Arsenic, and Aconita. Including the trials of Tawell, W. Palmer, Dove, Madeline Smith, Dr. Pritchard, Smethurst, and Dr. Lamson, with chemical introduction and notes on the poisons used — John Shaqi
Reports of Trials for Murder by Poisoning;: by Prussic Acid, Strychnia, Antimony, Arsenic, and Aconita. Including the trials of Tawell, W. Palmer, Dove, Madeline Smith, Dr. Pritchard, Smethurst, and Dr. Lamson, with chemical introduction and notes on the poisons usedBrowne, G. Lathom (George Lathom)
Science
Reports of Trials for Murder by Poisoning;: by Prussic Acid, Strychnia, Antimony, Arsenic, and Aconita. Including the trials of Tawell, W. Palmer, Dove, Madeline Smith, Dr. Pritchard, Smethurst, and Dr. Lamson, with chemical introduction and notes on the poisons used
Browne, G. Lathom (George Lathom)
Medical jurisprudence -- Great Britain; Poisons; Trials (Murder) -- Great Britain; Trials (Poisoning) -- Great Britain
7. _Animal charcoal_, previously purified by hydrochloric acid and
thorough washing with water, when digested with neutral or alkaline
solutions of alkaloids, not too dilute, absorbs them from the liquid.
The charcoal, washed twice or thrice with small quantities of water,
is dried at a moderate temperature, and boiled with strong alcohol,
which extracts the alkaloid. This process has been used for separating
picrotoxin from beer, but has the inconvenience that the alkaloid is
liable to gradual oxidation within the pores of the charcoal, and that
the separation is never complete. It is this property that has caused
charcoal to be recommended as an antidote in poisoning.
8. All alkaloids form with _platinic chloride_ double salts of more or
less sparing solubility. These precipitates, washed, dried and weighed,
and then burnt, leave metallic platinum, the amount of which yields
a clue to the composition of the base. But aconitine and narcotine
are only thrown down from concentrated solutions, and a few are not
precipitated at all. Hence this test is of only occasional value in
toxicological work. The same may be said of _auric chloride_.
9. _Tannin_ or tannic acid, a moderately strong solution in water,
throws down most alkaloids. Coffee and tea, and other tannin-containing
infusions, have, therefore, been used as antidotes with dubious
success. As a test it is not distinctive.
10. _Phospho-antimonic acid_ (Schultze), prepared by mixing antimony
pentachloride with ordinary sodium phosphate and decanting the clear
liquid, gives whitish amorphous precipitates with alkaloids.
11. _Silico-tungstic acid_ is prepared by boiling commercial tungstate
of soda with fresh gelatinous silica. Filter and allow to crystallize.
This gives precipitates with very dilute solutions of alkaloids, but it
is also precipitated by ammonium chloride (Godefroy, Arch. d. Pharm.,
Nov. 1879). Zaubenheimer recommends it as a most delicate test: the
precipitate may be decomposed by soda or potash, and the base extracted
by ether-chloroform.
12. Auric chloride, palladious chloride, and mercuric chloride have
been proposed, but are not of much use. Potassium chromate and
sulphocyanide, and sodium nitroprusside give somewhat insoluble
precipitates, generally crystalline and of characteristic appearance
under the microscope. These tests should be strong, and must be used in
small quantity.
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