Calling one morning on an intimate friend of mine at _Paris_, I found him involved in the deepest melancholy. On enquiring into the cause, he acquainted me, that having been so long in the hands of _Daran_ for the cure of a gleet, he at last thought himself free of it, when, on a sudden, he was cruelly disappointed. Upon which he begged of me to give him any advice in my power, his situation being extremely critical on the point of marriage with a young lady of fortune whom he loved, and with whom he could not bear the thought of engaging, while under so cruel a circumstance. On this I said to him all that occurred to me just then for his consolation. After I had left him I could not help reflecting on his melancholy condition, and thinking how possibly he could be extricated out of it. The best way that offered to my mind was his cure. I indeed considered suppuration as the only method to effect it. But not accustomed indiscriminately to adopt a method as soon as it is extolled, much less to follow it blindly, I enquired into the reasons of the frequent inefficacy of the usual practice, and soon was made sensible of them. After mature consideration, I called upon my friend, and proposed to attempt his cure. He readily agreed. The same day he took an apartment next to mine. I immediately began his treatment, attended him closely, and by suppuration properly conducted, was radically cured in seven weeks. Some months after, two of his acquaintances left incurable by _Daran_, applied to me, requesting my assistance, and both were cured in eleven weeks time. But here is not the place for enumerating cures performed by my method; I therefore proceed to point out the defects of the actual practice of preparing and using bougies to cure gleets, and shall communicate the proper way to improve it, so as never to fail the intention. The actual method of treating gleets is frequently unsuccessful, because defective. The first defect is the hardiness of the suppurative, common bougies are made with. This is obvious from the structure of the affected parts. The internal tunic of the urethra, although ever irritated in a virulent gonorrhœa, is seldom the seat of the disease. Its seat is commonly the glandular tunic beneath the muscular, as is shewn by the abundance of the suppuration, and more plainly by dissecting. In such case, it is evident, that a common bougie introduced in the urethra, acting immediately on the internal tunic alone, cannot cause but an imperfect suppuration of the ulcerated parts, and consequently cannot perfect the cure. If so, when the ulcers of the glandular tunic lie at the entrance of the lacunes in the internal tunic; how much more when the corroding virus has extended its seat, and produced a kind of sinusses, as is always the case in inveterate gleets! Another defect in common bougies is a want of degradation in their suppurative virtue.