The nutrition of the mother certainly plays a leading part in the development of the ovum within her body. The different experiments which breeders have made, and the observations which have repeatedly shown in the case of the invertebrata (v. Berlepsch, ‘_Die Biene und ihre Zucht_,’ second edition; Landois, ‘_Physiologie_’), a connection between food and the development of sex leave no doubt that, in the case of the human subject also, a certain diet of the mother would not be without influence on the ovum developing within her. Here, however, in the case of the ripening of the ovum, according to my opinion, the result does not depend on the diet alone, but rather on the process of metabolism in the mother. How the physiological combustion goes on in the organism, and what changes take place in it, in consequence of the altered diet, until the sugar entirely disappears, is in the case of human beings of the highest importance, and furnishes an index of the consequences. In individual cases the diet is directed in accordance with the results that show how the food has been assimilated and does not depend upon these alone. In other words, whether the mother eats much meat is a secondary consideration. Whether and how the food taken is completely made use of in the process of combustion--that is a matter of importance for the purpose we have in view. Any one, who keeps before him the fundamental principles of this theory, will see plainly that it is possible, under certain circumstances, to procure male progeny by means of the influence we have indicated. _The wish to have female progeny is a desire for the gratification of which it is not at present possible to give any directions._ * * * * * In connection with all that I have already said I will here mention that the method which I employed to procure the ripening of an ovum for male progeny in cases where I had previously found sugar normally present, which served as an indication for the application of my treatment, I attempted to apply also in the case of individuals with whom no trace of sugar was to be found. The method of proceeding, judging by my experiences thus far, should be as follows. First of all, it must be elicited whether any special disease exists, and especially any that indicates anomalies in the metabolism. Of course capacity for generation and the possibility of conception are presupposed. If the history of the case shows no circumstances that would hinder the application of the method, we inform the patient that she must furnish us with the urine necessary for the occasional examination. It is best to use for this purpose a urine glass marked in grammes and containing two litres, in which the urine of twenty-four hours is to be collected.