An important conference upon cholera was held in Berlin, at the Imperial Board of Health, on the evening of July 26. There were present Drs. Von Bergman, Coler, Eulenberg, B. Frankel, Gaffky, Hirsch, Koch, Leyden, S. Neumann, Pistor, Schubert, Skrezcka, Struck, Virchow, and Wollfhugel. The conference had been called at the instance of the Berlin Medical Society, whose President, Professor Virchow, explained that it was thought advisable Dr. Koch should in the first instance give a demonstration of his work before a smaller body than the whole Society, so that the proceedings might be fully reported in the medical press. He mentioned that Herr Director Lucanus and President Sydow had expressed their regret at being unable to be present, as well as many others, including Drs. Von Lauer, Von Frerichs, Mehlhausen, and Kersandt. Dr. Koch first showed various specimens of the bacilli and their method of preparation (see _Berliner Klinische Wochenschrift_, August 4). This resembles that for the tubercle bacillus, viz., drying on a cover glass and staining with fuchsin or methyl-olin. Koch then gave a history of his work while in Egypt and India. His post-mortem examinations led him to believe that the intestines were the nidus of the disease. At first his microscopical examinations were unsatisfactory, but finally he got fresh dejecta and acute cases, and then discovered the comma bacillus. This, he said, is smaller than the tubercle bacillus, being only about half or at most two-thirds the size of the latter, but much more plump, thicker, and slightly curved. As a rule, the curve is no more than that of a comma (,), but sometimes it assumes a semicircular shape, and he has seen it forming a double curve like an S; these two variations from the normal being suggestive of the junction of two individual bacilli. In cultures there always appears a remarkably free development of comma-shaped bacilli.